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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Dihexa for Sale > Dihexa CAS 1401708-83-5 99% Purity Neuroprotective Peptide Powder Cognitive Enhancement Raw Material
Dihexa CAS 1401708-83-5 99% Purity Neuroprotective Peptide Powder Cognitive Enhancement Raw Material buy - large image1
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Dihexa CAS 1401708-83-5 99% Purity Neuroprotective Peptide Powder Cognitive Enhancement Raw Material buy - image6

Dihexa CAS 1401708-83-5 99% Purity Neuroprotective Peptide Powder Cognitive Enhancement Raw Material

179 Inquiries

Unit Price:

$30-35/UNIT FOB

Get Latest Price
CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

HB

Packaging:

5mg 10mg/ vial ,10vials/box

Sample Available:

Yes

Price valid (until):

2027-01-20

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment
Average Lead Time:
1 days
Qualification:
Main Products:

GLP-1,Retatrutide,Selank,Tirzepatide

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Name: Jane
    Whatsapp/WeChat: +852 95478358
    Email: jane@yingliantech.cn

    Dihexa, also known as PNB-0408, is a potent and orally active neuroprotective peptide with CAS number 1401708-83-5. It is a highly stable angiotensin IV analog with excellent blood-brain barrier permeability.

    This product can effectively activate HGF/c-Met signaling pathway, promote synaptogenesis and neuronal repair. It shows great potential in improving learning and memory, protecting neurons, and relieving cognitive impairment.

    Our Dihexa is high purity 98% / 99%, white fine powder, stable batch quality, strict HPLC testing. We can provide COA, HPLC, MSDS for customer reference. Suitable for neuroscience research, pharmaceutical intermediate and cognitive health research raw materials.
    Items Specifications
    Product Name
    Dihexa
    CAS No. 1401708-83-5
    Model No. Petide
    Purity >99%
    Shelf Life 2 Years
    State Powder
    Storage Cool and Dry Place
    shipment within 48h after payment
    MOQ 1 box

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      Company profile  


    Yinglian Technology Co., Ltd. (Jinzhou Hongbai Technology Co., Ltd. Subsidiary branch company) was established in 2018 ,We mainly engage in peptides, synthetic peptide amino acids, beauty and weight - loss products, as well as raw materials for beauty and freckle - removing cosmetics, all of which are of reliable quality. Committed to strict quality control and thoughtful customer service, our experienced staff are always ready to discuss your requirements to ensure customer satisfaction. "Quality first, service foremost" summarizes our business philosophy. We firmly believe that prioritizing quality in all aspects of operations and providing excellent service lay the foundation for long - term success. Our mission is to lead the advancement of biotechnology by consistently adhering to the highest standards of quality and service. We hope to contribute to improving global health through innovation and excellence. We focus on high quality, competitive prices, flexible order quantities and timely delivery. Our products are mainly exported to European countries, the United Kingdom, the United States, Canada and Australia. We have extensive export experience and have never encountered any customs clearance issues. By focusing on sourcing materials of perfect quality and ensuring strict internal process control, our products have been widely recognized and trusted by users.

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      Why choose us  


    1.We are very experienced with this field;
    2.Good after-sales service
    3.100% quality guaranteed;
    4.Reasonable & competitive price, fast lead time.;
    5.Strong supply ability
    6.Made in China ,high credit guarantee.


      Packing  



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      Transportation  


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     FAQ 


    Q1: About the after-sale service
    A: After purchasing the products from our Lab, we have A professional technical team and after-sales team to serve you and solve all your problems in the future

    Q2:  I want to know more details about the product, how can I contact you?
    A: You can send us an email inquiry at any time. For more accurate quotes, I need the following information: product name, order quantity, receipt country, quality requirements, etc.

    Q3: Can I get some samples?
    A:Yes, we can provide samples, but the customer will pay the shipping cost.

    Q4: About the seller's response
    A: We will respond to your message in a timely manner. We guarantee to respond to you within 24 hour


    Q5: What is your MOQ?
    A: The minimum quantity we can order is 1 box.

    Q6: Can you give me a discount price?
    A:Surely,It depend on your quantity. 

    Q7:  How to preserve peptides after receiving them?
    A:Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2 ° C - 8 ° C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20 ° C or -80 ° C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

    ECHEMI Editorial Reference

    Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

    Basic Info
    Product Name:

    Dihexa

    Other Name:

    L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

    CAS No.:

    1401708-83-5

    Molecular Formula:

    C27H44N4O5

    InChIKeys:

    InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

    Molecular Weight:

    504.7

    Exact Mass:

    504.66

    Categories:

    Other Chemical Drugs

    Characteristics
    Density:

    1.111±0.06 g/cm3(Predicted)

    Boiling Point:

    866.2±65.0 °C(Predicted)

    Research
    Class:

    Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

    Status:

    Research compound — Not FDA approved

    Mechanism:

    A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

    EC50 (HGF Binding KD):

    65 pM

    Activity note:

    Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

    Source:

    Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

    Clinical Development:

    NCT04488419

    References
    PubChem:

    PubChem

    UNII:

    9WYX65A5C2

    Disclaimer:

    Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    GLP-1,Retatrutide,Selank,Tirzepatide

    Location:

    Room 2012, No. 6-143, Section 2, Shanghai Road, Guta District, Jinzhou City, Liaoning Province

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment

    Average lead Time:

    1 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    5-10

    Year of Establishment:

    2024

    Yinglian Technology Co., Ltd. ( Jinzhou Hongbai Technology Co., Ltd. Subsidiary branch company ) .We mainly engage in peptides, synthetic peptide amino acids, beauty and weight - loss products, as well as raw materials for beauty and freckle - removing cosmetics, all of which are of reliable quality. Committed to strict quality control and thoughtful customer service, our experienced staff are always ready to discuss your requirements to ensure customer satisfaction. "Quality first, service foremost" summarizes our business philosophy. We firmly believe that prioritizing quality in all aspects of operations and providing excellent service lay the foundation for long - term success. Our mission is to lead the advancement of biotechnology by consistently adhering to the highest standards of quality and service. We hope to contribute to improving global health through innovation and excellence. We focus on high quality, competitive prices, flexible order quantities and timely delivery. Our products are mainly exported to European countries, the United Kingdom, the United States, Canada and Australia. We have extensive export experience and have never encountered any customs clearance issues. By focusing on sourcing materials of perfect quality and ensuring strict internal process control, our products have been widely recognized and trusted by users.

  • Inquiry History
    179 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

    Dihexa lyophilized 1401708-83-5

    1  Aug 23, 2026
    Canada

    Dihexa 1401708-83-5

    1 G Mar 8, 2026
    Bulgaria

    Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5

    10 G May 27, 2025
    Australia

    Dihexa

    30 G Oct 19, 2026
    United States

    Dihexa

    500 G Aug 19, 2026
    United States

    Dihexa

    25 G Jan 26, 2025
    Russia

    DIHEXA

    50.00 G Aug 14, 2024
    Australia

    Dihexa

    2 G Oct 19, 2026
    United States

    dihexa

    10 MG Sep 28, 2026
    Spain

    Dihexa

    100 MG Aug 30, 2026
    United Arab Emirates

    Diheza

    1 G Aug 28, 2026
    Canada

    Dihexa

    130  Aug 12, 2026
    Brazil

    dihexa

    90 MG Aug 4, 2026
    United States

    Dihexa raw powder

    10 G Jul 26, 2026
    Singapore

    Dihexa

    10 PCS Jul 15, 2026
    United States

    Dihexa

    1 G Jul 11, 2026
    Sweden

    Dihexa

    10 PCS Jul 8, 2026
    Australia

    Dihexa

    1 MT Jul 2, 2026
    United States

    Dihexa

    10 G Jun 14, 2026
    Germany

    Dihexa

    1 G May 25, 2026
    Post an enquiry for this product
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