1. Basic Molecular Parameters (Industry Standard)
Full Name: Cortagen (Cerebral Cortex Targeted Bioregulatory Tetrapeptide)
Amino Acid Sequence: H-Ala-Glu-Asp-Pro-OH (Abbreviation: AEDP, Tetrapeptide)
Molecular Formula: C₁₇H₂₆N₄O₉
Molecular Weight: 430.41 g/mol
CAS Number: 335591-03-2
Appearance: Sterile lyophilized white powder, sealed vial packaging (main specifications: 10mg / 20mg per vial)
Purity: ≥98% as verified by HPLC; full COA, HPLC chromatogram and MSDS are supplied with each batch
R&D Background: A tissue-specific bioregulatory peptide developed by Professor Vladimir Khavinson at the Institute of Bioregulation and Gerontology, Saint Petersburg, Russia. Synthesized based on amino acid extraction from mammalian cerebral cortex, specially designed for epigenetic gene regulation of central nervous system cells.
2. Core Mechanism of Action
Cortagen penetrates the nucleus of neurons and glial cells, remodels chromatin architecture, and reactivates functional genes silenced by cellular aging:
- Decondense compact heterochromatin, restore transcriptional accessibility of age-suppressed neural genes;
- Upregulate expression of neurotrophic factors including BDNF, NGF and NT-3, boost neuronal protein synthesis and axonal regeneration;
- Balance excitatory/inhibitory neurotransmitter pathways (glutamate & GABA) to stabilize cortical neural electrical activity;
- Activate intracellular antioxidant enzymes to mitigate neuronal oxidative damage and lipid peroxidation;
- Suppress excessive microglial activation and pro-inflammatory cytokines to relieve neuroinflammation;
- Regulate lymphocyte gene expression to coordinate central nervous and peripheral immune functions;
- Accelerate myelin sheath repair of damaged nerve fibers and restore neural signal conduction efficiency.
3. Core Research Efficacy (For Laboratory Research Only)
Central & Peripheral Nerve Repair
Promote axonal regrowth and remyelination after cerebral ischemia, traumatic brain injury and peripheral nerve lesions; suitable for cell & animal models studying nerve injury recovery.
Anti-Aging & Cognitive Regulation
Reverse age-induced gene silencing in cortical neurons; improve learning, memory and object recognition capacity in aged preclinical models for senile cognitive decline research.
Neuroprotective & Antioxidant Study
Counteract excitotoxicity and oxidative stress in neural tissue; serve as core reagent for screening anti-neurodegeneration substances.
Neuro-Immune Modulation
Regulate cross-talk between central nerve system and immune cells; support experiments on neuroinflammation and autoimmune neurological disorders.
Supplementary Compliance Disclaimer
This product is laboratory research reagent only. It shall not be applied to human injection, oral administration or clinical medical treatment. All functional descriptions are derived from preclinical cell and animal experimental data, not therapeutic medical claims.
Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.
Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.
Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.
We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together. We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.
We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.
We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.
United States
