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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Acetyl Octapeptide-1 for Sale > snap-8 99%Freeze-dried powder In stock Minimum Order Hot Selling
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snap-8 99%Freeze-dried powder In stock Minimum Order Hot Selling

TDS 13 Inquiries

Unit Price:

$33/UNIT FOB

Get Latest Price
CAS No.:

868844-74-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

TianJin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2027-08-15

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Basic Parameter Information

    Full Name: SNAP-8, Scientific Name: Acetyl Octapeptide-3

    Amino Acid Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂ (Single letter abbreviation: Ac-EEMQRRAD-NH₂, N-terminal acetylation, C-terminal amidation octapeptide)

    Molecular Formula: C₄₁H₇₀N₁₆O₁₆S

    Molecular Weight: 1075.16 g/mol

    CAS Number: 868844-74-0

    Appearance: Sterile lyophilized white powder, packaged in vials (main specifications: 10mg / 50mg / 100mg)

    Purity: ≥99% as tested by HPLC, COA quality inspection report attached for each batch

    R&D Background: SNAP-8 was developed by Lipotec SA in Spain in the early 2000s, as a second-generation upgraded mimetic neuropeptide of Argireline (Acetyl Hexapeptide-8). It adds two extra amino acid residues on the basis of Argireline, with stronger competitive binding capacity and better enzymatic stability. SNAP-8 simulates the key fragment of endogenous SNAP-25 protein, interfering with SNARE complex assembly to inhibit neurotransmitter release. It is widely used in cosmetic raw material research, skin anti-aging cell experiments and transdermal delivery system preclinical studies.

    2. Core Mechanism of Action

    SNAP-8 penetrates the epidermis to reach dermal neuromuscular junctions, exerting mild muscle relaxation effect through competitive inhibition of SNARE complex formation without complete muscle paralysis:

    Mimic the binding domain of SNAP-25 protein, competitively occupy the binding site of syntaxin and synaptobrevin, block the complete assembly of ternary SNARE complex;

    Inhibit calcium-dependent synaptic vesicle fusion with presynaptic membrane, reduce the secretion of acetylcholine neurotransmitter at neuromuscular junctions;

    Weakly weaken facial muscle contraction intensity, relieve repeated micro-contraction of expression muscles (frontal muscle, orbicularis oculi, zygomatic muscle);

    N-terminal acetylation and C-terminal amidation structural modification resist protease degradation, extend skin surface action time up to 12–24 hours;

    Improve the microenvironment of aged dermis, slightly upregulate collagen synthesis of dermal fibroblasts, auxiliary to repair fine lines caused by repeated muscle movement;

    Compatible with liposome, microneedle and transdermal penetration enhancers, can reach dermal target layer 150–200μm below epidermis for sustained efficacy.

    3. Core Research Efficacy (For Research Laboratory Use Only)

    Dynamic Expression Line Improvement Research

    Reduce repetitive contraction of expression muscles, visibly fade forehead lines, crow’s feet, frown lines and nasolabial folds; core raw material for anti-wrinkle cosmetic formulation screening and 3D skin wrinkle model cell experiments. Continuous external application test data shows wrinkle depth reduction of 35%–63% after 28 days.

    Mild Neuromuscular Relaxation Research

    Different from high-potency paralyzing ingredients, SNAP-8 only moderately weaken contraction signals, suitable for mild anti-aging, sensitive skin and neck & décolletage wrinkle research models. Its efficacy is about 30% higher than the first-generation Argireline peptide.

    Transdermal Delivery & Cosmeceutical Formulation Study

    Common experimental raw material for serum, cream, gel and microcapsule carrier research; used to explore peptide skin penetration efficiency, sustained release technology and multi-peptide compound anti-aging formula matching.

    Dermal Anti-Aging Auxiliary Repair

    While relaxing muscles, stimulate fibroblast activity to promote type I collagen secretion, alleviate skin rough texture caused by long-term muscle traction, applied to aged skin barrier repair related cell tests.

    Compound Peptide Synergy Research

    Can compound with moisturizing peptides, antioxidant peptides and collagen-promoting peptides, widely used in multi-component composite anti-aging cosmetic efficacy evaluation experiments.
    Supplied as sterile lyophilized white powder, HPLC purity ≥99%, mainstream vial specifications: 10mg, 50mg, 100mg. Every batch is equipped with full COA, MSDS and HPLC chromatogram test documents.
    As an upgraded biomimetic anti-wrinkle neuropeptide, SNAP-8 targets the upstream neurotransmission link of wrinkle formation. It suppresses excessive facial muscle micro-contraction by interfering SNARE complex, achieves non-invasive mild smoothing of dynamic lines, with better stability and stronger activity than traditional hexapeptide Argireline. It is a standard research reagent for cosmetic peptide laboratories to develop needle-free muscle-relaxing anti-aging skincare ingredients.
    It serves as essential research material for in-vitro skin cell culture, 3D skin tissue model and formulation development experiments covering cosmetic anti-wrinkle, transdermal penetration technology, compound peptide efficacy verification and dermis aging research.
    Note: For laboratory research & cosmetic raw material development use only, not approved for human clinical therapeutic treatment.
    We maintain sufficient stable stock, complete export certification documents, door-to-door double customs clearance service with full real-time tracking of all shipments.


      About us  


              Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.

             Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
           At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
             Our Commitment: Integrity, efficiency, and transparency in every transaction.


      Why choose us  


          Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.

               We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.

               We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.

              We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.

              We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.


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      Our Advantages

     


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    ECHEMI Editorial Reference

    Acetyl Octapeptide-1, commonly known by its trade name SNAP-8, is a synthetic bioactive peptide widely utilized in the cosmetic and skincare industries for its potent anti-wrinkle properties. It is an extended version of the well-known Argireline (Acetyl Hexapeptide-3), designed to offer enhanced stability and efficacy in reducing dynamic facial lines.

    Research & Reference Note

    snap-8 99%Freeze-dried powder In stock Minimum Order Hot Selling is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals

    Certificates
    • snap-8 99%Freeze-dried powder  In stock Minimum Order Hot Selling Certificates 1 TDS

    Basic Info
    Product Name:

    Acetyl Octapeptide-1

    Other Name:

    N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alpha-asparagine;SNAP-8(AcetylGlutamylHeptapeptide-3);AcetylGluChemicalbooktaMylHeptapeptide-3;AcetylOctapeptide-3;AcetylGlutaMylOctapeptide-3;AcetylOctapetpide-3;snap-8/AcetylOctapeptide-3/AcetylGlutamylHeptapeptide-3;AcetylOctapeptide-8

    CAS No.:

    868844-74-0

    Molecular Formula:

    C41H70N16O16S

    InChIKeys:

    KMACPCJUCHVVGP-FNRPHRCSSA-N

    Molecular Weight:

    1075.16

    Exact Mass:

    1074.487671

    DSSTox ID:

    DTXSID70235943

    Characteristics
    PSA:

    585

    XLogP3:

    -7.7

    Density:

    1.56

    Refractive Index:

    1.665

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

    Location:

    Hefei, Provincia de Anhui

    Year of Establishment:

    2026

  • Inquiry History
    13 Inquiries
    Country Product Purchase Quantity Date Posted
    Australia

    Acetyl Octapeptide-1

    1 KG Oct 17, 2026
    United States

    Acetyl Octapeptide-3

    10 G Jun 23, 2026
    United States

    Acetyl Octapeptide

    10 G Jun 22, 2026
    United States

    snap8

    20 MG Jun 3, 2026
    United States

    SNAP-8

    100 G Apr 20, 2026
    Australia

    SNAP-8

    50 KG Apr 20, 2026
    United States

    Snap8

    10 G Apr 17, 2026
    Malaysia

    snap-8

    10 MG Jan 27, 2026
    Brazil

    Acetyl Octapeptide-1

    10 KG Nov 19, 2024
    Italy

    Antirughe SNAP-8 snap 8 peptide Pure Acetil Octapeptide-3

    5 KG Nov 16, 2024
    United States

    Snap 8

    100 MT Jul 6, 2024
    United States

    Snap 8

    1 G Jun 25, 2024
    South Africa

    SNAP 8

    100 MT Feb 28, 2024
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