Sodium Caprylate - Covvalent

Sodium Caprylate (CAS 1984-06-1), also known as Sodium Octanoate and Caprylic acid sodium salt, is a compendially qualified pharmaceutical excipient manufactured by Covvalent at its cGMP-compliant facility in India to Ph. Eur. and USP-NF specifications. Assay 99.0–101.0% (anhydrous basis). Molecular formula C8H15NaO2, molecular weight 166.19 g/mol.

Sodium Caprylate is the dominant stabiliser used in Human Albumin Solution (HAS) manufacturing worldwide. The medium-chain fatty acid sodium salt occupies the high-affinity hydrophobic IIA and IIB binding pockets of human serum albumin (Sudlow sites), providing thermodynamic stabilisation against heat-induced conformational denaturation during pasteurisation. Independently, at physiological concentrations it exerts antimicrobial activity against Gram-positive bacteria, mycoplasma, and enveloped viruses — a dual function exploited in plasma fractionation workflows for both stabilisation and pathogen reduction.

Covvalent manufactures Sodium Caprylate with full analytical characterisation to cGMP, supplying with CoA, MSDS, and regulatory documentation for US FDA and EMA regulated market submissions.