PNC-27 99%+ High Purity Peptide Powder Multiple Specifications: 5 mg 10 mg per vial CAS 1159861-00-3

What Is PNC-27?
PNC-27 is a 32-amino acid synthetic peptide that functions as a chimeric molecule combining two functional domains: an HDM-2-binding domain corresponding to residues 12-26 of the human p53 protein, and a cell-penetrating peptide (CPP) leader sequence derived from the antennapedia protein. The peptide consists of the amino acid sequence: Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly, with a molecular weight of approximately 4031.7 Daltons. In laboratory studies, PNC-27 has been shown to bind to the HDM-2 protein when expressed in the plasma membrane of target cells, leading to the formation of transmembrane pores and subsequent cellular disruption. This effect has been observed in various laboratory cell line models. It is important to note that PNC-27 is NOT an approved therapeutic agent and is strictly a research tool for controlled laboratory investigations. The peptide has been referenced in multiple peer-reviewed scientific publications studying protein interactions and membrane biology. Our PNC-27 is supplied as a high-purity (99%+) lyophilized powder, available in 5 mg and 10 mg vials, with CAS 1159861-00-3.

Why Choose Our PNC-27 with Multiple Specifications?
Pick the right amount for your research needs. The 5 mg vial is ideal for small-scale experiments, pilot studies, or preliminary investigations. The 10 mg vial suits more extensive research protocols or larger-scale laboratory studies. Choose the size that matches your project requirements.

Well-documented in scientific literature. PNC-27 has been studied in multiple peer-reviewed publications that have characterized its amino acid structure, binding specificity, and mechanism of action. Researchers can reference this body of work when designing and interpreting their studies.

Selective targeting mechanism for controlled research. The mechanism of PNC-27 — binding to specific cell surface proteins to induce membrane pore formation — offers researchers a well-defined tool for studying protein-protein interactions and the effects of membrane disruption in controlled laboratory systems.

High purity ensures reliable, reproducible results. Our ≥99% purity minimizes variability across experiments, giving researchers confidence in their data and the reproducibility of their findings.

Same high purity across both sizes. Whether you order 5 mg or 10 mg, you receive the same 99%+ purity, same COA traceability, and same rigorous quality standards.

Stringent quality control. Every batch is tested using HPLC to confirm purity and correct identity. Complete Certificate of Analysis (COA) documentation is available upon request.

Ready to ship with cold chain. Due to the specific storage requirements of this peptide, we ship PNC-27 under cold chain conditions (with ice packs) to maintain stability during transit. Vacuum-sealed, discreet packaging ensures product integrity.

Sales manager:  Eira
whatsapp：+8619304441463
Email:  sales01@cnspks.com

1. Advanced Manufacturing Capabilities

Cutting-Edge Facilities: High-precision equipment ensuring purity and bioactivity.

Scalable Production: From milligram-scale research peptides to multi-kilogram industrial batches.

2. Innovation & Customer Commitment

Reliable Supply Chain: Competitive pricing & timely global delivery.

Global Reach: Trusted by researchers, pharmaceutical firms & industrial clients worldwide.

1. Expertise in Peptide Synthesis

Extensive Experience: 7 Years of expertise in synthetic peptide development.

Skilled Team: Experts in solid-phase and liquid-phase synthesis.

2. Advanced Manufacturing Capabilities

Cutting-Edge Facilities: High-precision equipment ensuring purity and bioactivity.

Scalable Production: From milligram-scale research peptides to multi-kilogram industrial batches.

3. Innovation & Customer Commitment

Reliable Supply Chain: Competitive pricing & timely global delivery.

Global Reach: Trusted by researchers, pharmaceutical firms & industrial clients worldwide.

4. Ultra-High Purity
Each batch is synthesized and purified to >99% purity (HPLC), ensuring reliable and reproducible results in sensitive experiments.

5.Accurate Dosing & Consistency
Our peptides are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.

6.Endotoxin-Free & Sterile Processing
Manufactured in a cleanroom environment, our peptides are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.