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2,4-Thiazolidinedione2295-31-0

Name: 2,4-Thiazolidinedione2295-31-0
Brand: OORENT
SKU: pr2607081591
Price: 33 USD
Availability: InStock

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Unit Price:

$33-34/MT FOB

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CAS No.:

2295-31-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

OORENT

Packaging:

vial

Price valid (until):

2026-08-08

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

2,4-Thiazolidinedione Basic information

Product Name:	2,4-Thiazolidinedione
Synonyms:	2,4-Thiazolidinedione, 99% 100GR;2,4-Thiazolidinedione, 99% 25GR;thiazolidin-2,4-dione;2,4-Thiazolidinedione technical grade, 90%;2, 4 - Margaret diketone;OTAVA-BB BB7112440002;TZD;TIMTEC-BB SBB000047
CAS:	2295-31-0
MF:	C3H3NO2S
MW:	117.13
EINECS:	218-941-2
Product Categories:	Starting Raw Materials & Intermediates;PHARMACEUTICAL INTERMEDIATES;Sulfur compounds;blocks;Heterocycles;Sulphur Derivatives;Thiazoles;Drug Intermediates;(intermedate of rosiglitazone);All Inhibitors;Diabetes;Inhibitors;Ring Systems;Building Blocks;Heterocyclic Building Blocks;bc0001
Mol File:	2295-31-0.mol

2,4-Thiazolidinedione Chemical Properties

Melting point	125-127 °C (lit.)
Boiling point	178-179 °C (19 mmHg)
density	1.408 (estimate)
vapor pressure	0Pa at 25℃
refractive index	1.5130 (estimate)
Fp	178-179°C/19mm
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	6.50±0.10(Predicted)
form	Crystalline Powder
color	Slightly yellow
Water Solubility	Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
BRN	110700
InChI	1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
InChIKey	ZOBPZXTWZATXDG-UHFFFAOYSA-N
SMILES	O=C1CSC(=O)N1
LogP	-0.29 at 25℃
CAS DataBase Reference	2295-31-0(CAS DataBase Reference)
NIST Chemistry Reference	2,4-Thiazolidinedione(2295-31-0)
EPA Substance Registry System	2,4-Thiazolidinedione (2295-31-0)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
RTECS	XJ5775000
TSCA	TSCA listed
HazardClass	IRRITANT
HS Code	29341000
Storage Class	11 - Combustible Solids

MSDS Information

Provider	Language
Thiazolidine-2,4-dione	English
ACROS	English
SigmaAldrich	English
ALFA	English

2,4-Thiazolidinedione Usage And Synthesis

Chemical Properties	White to Off-White Powder
Uses	Inhibitor of enzyme
Uses	2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.
Definition	ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.
General Description	2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.
Flammability and Explosibility	Not classified

2,4-Thiazolidinedione Preparation Products And Raw materials

Raw materials	Rhodanine
Preparation Products	Thiazole-5-carboxaldehyde-->Thiazole-4-carboxaldehyde-->Rosiglitazone-->2,4-Dibromothiazole-->S49076-->2,4-DIBROMO-THIAZOLE-5-CARBALDEHYDE,97%-->(2,4-DIOXO-1,3-THIAZOLIDIN-3-YL)ACETIC ACID-->2,4-Dichlorothiazole-->5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione-->2,4-Dichloro-5-thiazolecarboxaldehyde

Pls input... Shop TRANS-2-DECEN-1-OL18409-18-2-Detailed Image 2

Basic Info

Product Name:

Thiazolidinedione

Other Name:

2,4-Thiazolidinedione;Thiazolidinedione;2-Thiazolin-4-one,2-hydroxy-;2,4-Dioxothiazolidine;2,4(3H,5H)-Thiazoledione;U 25560;NSC 6745;Thiazole-2,4-dione;2,4-Dioxo-1,3-thiazolidine;Thiazolidin-2,4-dione;2-Hydroxy-4,5-dihydro-1,3-thiazol-4-one

CAS No.:

2295-31-0

Molecular Formula:

C3H3NO2S

InChIKeys:

InChIKey=ZOBPZXTWZATXDG-UHFFFAOYSA-N

Molecular Weight:

117.122

Exact Mass:

117.13

EC Number:

218-941-2

UNII:

AA68LXK93C

NSC Number:

6745

DSSTox ID:

DTXSID5040623

HScode:

2934999090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

71.5

XLogP3:

0.1

Appearance:

White to Off-White Powder

Density:

1.5±0.1 g/cm3

Melting Point:

128 °C

Boiling Point:

305.7°C at 760 mmHg

Flash Point:

138.7±19.3 °C

Refractive Index:

1.577

Water Solubility:

Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.

Storage Conditions:

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Vapor Pressure:

0.000809mmHg at 25°C

See More Thiazolidinedione Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Thiazolidinedione Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	2,4-Thiazolidinedione	100 KG	Jun 12, 2024

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