—— Product Specifications ——

—— Product Detail ——

• • • • • • • • • • • Product Overview

                      2,6-Dichloro-4-(trifluoromethyl)aniline is a halogenated aniline derivative with the molecular formula C₇H₄Cl₂F₃N and a molecular weight of 230.01 g/mol. This white to pale yellow crystalline powder features an aniline core substituted with two chlorine atoms at the 2 and 6 positions and a trifluoromethyl group at the 4 position, making it a valuable building block in pharmaceutical and agrochemical synthesis.

                      The compound's distinct substitution pattern combines electron-withdrawing groups (chlorine and trifluoromethyl) with an amino group, providing unique electronic properties that influence its reactivity and biological activity. It serves as a key intermediate in the synthesis of various bioactive molecules, particularly in the development of crop protection agents and pharmaceutical compounds targeting multiple therapeutic areas.

                      Synthetic Process

                      2,6-Dichloro-4-(trifluoromethyl)aniline is synthesized through the following routes:

                      • Chlorination of 4-(trifluoromethyl)aniline: 4-(Trifluoromethyl)aniline is chlorinated using chlorine gas or a chlorinating agent (such as N-chlorosuccinimide) under controlled conditions to introduce chlorine atoms at the 2 and 6 positions.

                      • Reduction of nitro derivative: 2,6-Dichloro-4-(trifluoromethyl)nitrobenzene is reduced using hydrogen and a metal catalyst or chemical reducing agents to yield the aniline derivative.

                      • Purification: The crude product is purified by recrystallization from ethanol or other suitable solvents.

                      Mechanism of Action / Application Principles

                      • Pharmaceutical Synthesis: Serves as a building block for the synthesis of various drug candidates, including kinase inhibitors, antiviral agents, and anti-inflammatory compounds.

                      • Agrochemical Research: Used as a key intermediate in the synthesis of herbicides, fungicides, and insecticides, particularly those containing the trifluoromethyl group.

                      • Fluorinated Compound Synthesis: The trifluoromethyl group imparts unique lipophilic and metabolic stability properties to target molecules.

                      • Material Science: Used in the synthesis of functional materials with fluorinated aromatic structures.

— C ompany Profile ——

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.