Name | β -Nicotinamide Mononucleotide |
CAS number | 1094-61-7 |
Description | Nicotinamide mononucleotide, also known as β-nicotinamide mononucleotide (NMN), is a synthetic substrate of coenzyme I. NMN is also used in anti-aging research.. |
Structural formula |  |
Molecular Formula | C11H15N2O8P |
Molecular Weight | 334.22 g/mol |
Appearance | White powder |
Quality Standard | 99% |
Storage Condition | -20°C |
Shelf Life | >2 years if stored properly |
Sample package | Aluminium foil bag |
Commercial package | Aluminium Tin, Fiber drum |
Origin | China |
β -Nicotinamide Mononucleotide (NMN, CAS 1094-61-7) is a biologically active nucleotide derivative and a key precursor of nicotinamide adenine dinucleotide (NAD+), an essential coenzyme involved in cellular energy metabolism and DNA repair. This high-purity compound is widely recognized for its anti-aging and cellular rejuvenation properties, making it a sought-after ingredient in nutraceutical and pharmaceutical applications. NMN is typically supplied as a white to off-white crystalline powder with ≥98% purity, rigorously tested for heavy metals, residual solvents, and microbiological contaminants to meet international standards (USP, EP, etc.).
Applications (Primary Uses)
NMN is extensively utilized in:
Anti-aging supplements: Boosts NAD+ levels to combat age-related metabolic decline and support mitochondrial function.
Pharmaceutical research: Investigated for potential therapeutic roles in neurodegenerative diseases (e.g., Alzheimer’s), diabetes, and cardiovascular health.
Cosmeceuticals: Incorporated into topical formulations for skin regeneration and UV protection.
Sports nutrition: Enhances endurance and recovery by optimizing cellular energy production.
Technical Considerations (Formulation & Stability)
For optimal performance:
Solubility: NMN is water-soluble (≥50 mg/mL at 25°C) but may require stabilizers (e.g., trehalose) in liquid formulations to prevent degradation.
pH Sensitivity: Stable at pH 3–7; avoid alkaline conditions (>pH 8) to prevent hydrolysis.
Storage: Preserve in airtight containers at -20°C for long-term stability (2+ years); room temperature is acceptable for short-term use (<6 months) with desiccants.
Safety & Regulatory Notes
GRAS status: Generally Recognized As Safe for oral use in specified doses (typical dosage: 100–500 mg/day).
Certifications: Available with ISO 9001, GMP, and third-party lab reports (HPLC, NMR, MS).
Precautions: Avoid direct sunlight/heat during handling; non-hygroscopic but moisture-sensitive. Pregnant/nursing women should consult physicians before use.
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