(Z)-Thiothixene
3313-26-6
98%
Shang Hai
1g/bag-1kg/bag
2026-07-15
SR17018
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Product Description
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Seller Information
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DescriptionECHEMI Editorial Reference(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.
Solid
Thiothixene is a N-methylpiperazine. It has a role as an anticoronaviral agent.|A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.|Thiothixene is a Typical Antipsychotic.|Thiothixene is a thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thereby decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. Thiothixene possesses weak affinity for the histamine H1 and alpha-adrenergic receptors.Basic Info-
Product Name:
(9Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
Other Name:9H-Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-,(9Z)-;Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-,(Z)-;9H-Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-,(Z)-;(9Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide;(Z)-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-Thioxanthene-2-sulfonamide;(Z)-Thiothixene
CAS No.:3313-26-6
Molecular Formula:C23H29N3O2S2
InChIKeys:InChIKey=GFBKORZTTCHDGY-UWVJOHFNSA-N
Molecular Weight:443.63
Exact Mass:443.63
EC Number:227-001-0
UNII:7318FJ13YJ
DSSTox ID:DTXSID6023658|DTXSID2091542|DTXSID30109999
NCI Thesaurus Code:C47752
Color/Form:White to tan crystals cis-, trans- mixture)|White to tan crystalline powder
ATC Code:N - Nervous system
HScode:2935904000
Categories:
Characteristics-
PSA:
77.5
XLogP3:3.78
Appearance:Solid
Density:1.269 g/cm3
Melting Point:cis isomer: 147.5-149 deg C; trans isomer 123-124.5 deg C; cis-trans mixture: 114-118 deg C
Boiling Point:599ºC at 760 mmHg
Flash Point:316.1ºC
Refractive Index:1.643
Water Solubility:>66.5 [ug/mL]
Storage Conditions:2-8°C
Vapor Pressure:2.56X10-12 mm Hg at 25 °C (est)
Odor:Practically odorless
Taste:Has very bitter taste
PH:pH: ready-to-use injection: from 2.5-3.5; constituted powder: from 2.3-3.7 /Thiothixene hydrochloride/
Henrys Law Constant:Henry's Law constant = 3.70X10-16 atm-cu m/mol at 25 °C (est)
Collision Cross Section:201.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:pH: ready-to-use injection: from 2.5-3.5; constituted powder: from 2.3-3.7 /Thiothixene hydrochloride/|White to nearly white crystalline powder. Has slight odor. Soluble in water; slightly soluble in chloroform. Practically insoluble in benzene, acetone, ether /Thiothixene hydrochloride/|Hydroxyl radical reaction reaction rate constant = 2.92X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 1.63X10-15 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
SR17018
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Location:
No. 8 Crown Road, Daguan District, Anqing City
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Country Product Purchase Quantity Date Posted Post an enquiry for this product