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Diethylstilbestrol

10 Inquiries

Unit Price: Get Latest Price
CAS No.:

56-53-1

Content:

98%

Port:

Shang Hai

Packaging:

1g/bag-1kg/bag

Price valid (until):

2026-07-15

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

SR17018

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


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    Product Name:Diethylstilbestrol Other Name:Diethylstilbestrol
    CAS No:56-53-1 Molecular Formula:C18H20O2

    Molecular Weight:268.35


    ECHEMI Editorial Reference
    Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.Target: Estrogen Receptor/ERRDiethylstilbestrol (DES), a synthetic estrogen that was used in pregnancy, is a prototype endocrine-disrupting chemical. Although prenatal exposure to DES is known to increase risks of vaginal/cervical adenocarcinoma and adverse reproductive outcomes in women, and urogenital anomalies in men, data on nonreproductive medical conditions are lac
    Diethylstilbestrol is an odorless tasteless white crystalline powder. (NTP, 1992)
    Diethylstilbestrol is an odorless tasteless white crystalline powder. (NTP, 1992)|Diethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor, an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor, an autophagy inducer and a calcium channel blocker. It is a polyphenol and an olefinic compound.|A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)|Diethylstilbestrol is a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.

    Basic Info
    Product Name:

    Diethylstilbestrol

    Other Name:

    Phenol,4,4′-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-;4,4′-Stilbenediol,α,α′-diethyl-,(E)-;Phenol,4,4′-(1,2-diethyl-1,2-ethenediyl)bis-,(E)-;4,4′-Stilbenediol,α,α′-diethyl-,trans-;4,4′-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[phenol];Bio-des;Comestrol;Cyren A;DEB;DES;Di-Estryl;trans-α,α′-Diethyl-4,4′-stilbenediol;Domestrol;Estilbin MCO;Estrobene;Estrosyn;Fonatol;Grafestrol;Hi-Bestrol;Microest;Milestrol;Oestrogenine;Oestromenin;Oestromensyl;Palestrol;Serral;Sexocretin;Sibol;Stil;Stilbestrol;Stilbetin;Stilboestroform;Stilboestrol;Stilkap;Stil-Rol;Synthoestrin;Syntofolin;trans-Diethylstilbestrol;Diethylstilbestrol;Stilboefral;α,α′-Diethyl-4,4′-stilbenediol;Dawe's destrol solution;4,4′-Dihydroxy-α,β-diethylstilbene;Bufon;Antigestil;Neo-Oestranol I;Distilbene;Iscovesco;Synestrin;(E)-4,4′-(1,2-Diethyl-1,2-ethenediyl)bisphenol;α,α′-Diethylstilbenediol;Dawe's destrol;DiBestrol 2 Premix;Rumestrol 2;Rumestrol 1;4,4′-Dihydroxydiethylstilbene;Cyren;Synthofolin;Pabestrol;Estromenin;Menostilbeen;Agostilben;DES (synthetic estrogen);trans-4,4′-Dihydroxy-α,β-diethylstilbene;(E)-3,4-Bis(4-hydroxyphenyl)-3-hexene;(E)-Diethylstilbestrol;Vagestrol;Oestromon;NSC 3070;Bertrol;trans-α,α′-Diethyl-4,4′-dihydroxystilbene;Estrogenine;8026-45-7;8028-09-9;8030-34-0;8049-42-1;8053-00-7

    CAS No.:

    56-53-1

    Molecular Formula:

    C18H20O2

    InChIKeys:

    InChIKey=RGLYKWWBQGJZGM-ISLYRVAYSA-N

    Molecular Weight:

    268.35

    Exact Mass:

    268.35

    EC Number:

    200-278-5

    UNII:

    731DCA35BT

    NSC Number:

    756736|3070

    UN Number:

    3077

    DSSTox ID:

    DTXSID3020465

    NCI Thesaurus Code:

    C433

    Color/Form:

    White crystalline powder|Small plates from benzene

    ATC Code:

    G - Genito urinary system and sex hormones|L - Antineoplastic and immunomodulating agents

    HScode:

    2942000000

    Categories:

    Characteristics
    PSA:

    40.5

    XLogP3:

    1.14

    Appearance:

    White to almost white Crystalline Powder

    Density:

    1.2

    Melting Point:

    169-172 °C

    Boiling Point:

    407.1±25.0 °C at 760 mmHg

    Flash Point:

    104°C c.c.

    Refractive Index:

    1.603

    Water Solubility:

    Practically insoluble in water;methanol: 0.1 g/mL, clear, faintly yellow

    Storage Conditions:

    0-6°C

    Vapor Pressure:

    Vapour pressure, Pa at 20°C: 20

    Vapor Density:

    Relative vapour density (air = 1): 5.3

    Toxicity:

    LD50 oral in rat: > 3gm/kg

    Explosive limit:

    vol% in air: 1.82.2

    Odor:

    Odorless

    Collision Cross Section:

    175.64 Ų [M-H]-

    Experimental Properties:

    CIS-ISOMER TENDS TO REVERT TO TRANS-FORM

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Hydrocarbons, Aliphatic Unsaturated

    Reactivity Profile:

    DIETHYLSTILBESTROL is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides (NTP, 1992).

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    Carcinogenicity, Category 1B

    Reproductive toxicity, Category 1B

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    H350 May cause cancer

    H360 May damage fertility or the unborn child

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    P273 Avoid release to the environment.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    SR17018

    Location:

    No. 8 Crown Road, Daguan District, Anqing City

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

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