High Purity Semaglutide 20mg 99% Research Peptide Lyophilized Powder CAS 910463-68-2
TDS 421 Inquiries
910463-68-2
Research Grade
99%
ShenZhen
XH
10 vials/kit, 10mg/vial or customized specification
Yes
2026-11-23
Retatrutide,Tirzepatide,Semaglutide,GHK-CU,NAD+,MOTS-C
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Product Details
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Seller Information
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History Price
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Inquiry History
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DescriptionECHEMI Editorial Reference
Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.
CertificatesBasic Info-
Product Name:
Semaglutide
Other Name:Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide
CAS No.:910463-68-2
Molecular Formula:C187H291N45O59
InChIKeys:DLSWIYLPEUIQAV-CCUURXOWSA-N
Molecular Weight:4113.57754
Exact Mass:4113.122087 g/mol
EC Number:203-405-2
Color/Form:White to off-white
Categories:
Characteristics-
PSA:
1650 Ų
XLogP3:5.44520
Critical Temperature & Pressure:Store at -20°C
Research-
Class:
GLP-1R agonist
Status:FDA-approved (Ozempic / Wegovy / Rybelsus)
Mechanism:Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.
Activity note:Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).
Source:Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI
Clinical Development:FDA:Ozempic, Wegovy, Rybelsus (approved 2017-12-05)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)
Disclaimer:Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Retatrutide,Tirzepatide,Semaglutide,GHK-CU,NAD+,MOTS-C
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Location:
Block 1, No. 205, Tongbao Road, Jiangdong Street, Yiwu City, Jinhua City, Zhejiang Province (within Zhejiang Juzhiyun Holding Co., Ltd., on the 4th floor of 2 buildings)
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Payment Terms:
TT against copy of documents,O/A,100% TT in advance
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Total Employees:
101-200
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Year of Establishment:
2026
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Weekly Price
The chart shows the price trend of the product in the past 12 months.
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Inquiry History421 Inquiries
Country Product Purchase Quantity Date Posted
United Kingdom
Semaglutide
1 G Oct 27, 2026
Belgium
Semaglutide
1 MT Oct 19, 2026
Chile
Semaglutide
10 MG Oct 16, 2026
Slovakia
semaglutide
10 MG Oct 15, 2026
Germany
Semaglutide
1 G Oct 14, 2026
South Africa
Semaglutide
10 MT Oct 11, 2026
United States
Semaglutide
1000 MT Oct 6, 2026
United States
Semaglutide
10 MT Sep 30, 2026
United States
Semaglutide
1000 KG Sep 30, 2026
United States
Semaglutide
30 MG Sep 28, 2026
United States
Semaglutide
10 MT Sep 25, 2026
Philippines
Semaglutide
10 MG Sep 20, 2026
India
Semaglutide
10 MG Sep 18, 2026
United Kingdom
Semaglutide - Reta - Tirz
100 MG Sep 17, 2026
United Kingdom
Semaglutide
10 G Sep 17, 2026
United Kingdom
Retatruide
1 MT Sep 15, 2026
United Kingdom
IGF-1 LR3
10 MT Aug 28, 2026
Paraguay
Semaglutide Freeze-dried Vial
1 KG Aug 27, 2026
United States
Semaglutide
2 MT Aug 25, 2026
United States
Semaglutide
1 MT Aug 24, 2026 Post an enquiry for this product
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