FOXO4-DRI Peptide | High Purity Research Peptide Supplier | Custom Synthesis|longevity|biomedical research

Mechanism of Action

① Targeting the FOXO4-p53 Pathway

Under normal conditions:

·In senescent cells, FOXO4 binds to p53
·FOXO4 helps maintain the survival of senescent cells
·FOXO4 prevents p53-mediated induction of cell death

After FOXO4-DRI enters the cell:

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FOXO4-DRI competitively binds to p53

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Disrupts the interaction between FOXO4 and p53

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Releases p53 signaling activity

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Induces apoptosis of senescent cells

② Selective Clearance of Senescent Cells 

Research suggests that the main characteristics of FOXO4-DRI include:

·Targeting senescent cells
·Reducing the accumulation of aging-related senescent cells
·Showing relatively limited effects on normal cells in research models

Therefore, FOXO4-DRI is known as:

Senolytic peptide (senescent cell clearance peptide)

Research Applications

① Cellular Senescence Research

Main research focuses include:

Mechanisms of senescent cell formation
SASP (Senescence-Associated Secretory Phenotype)
Senescent cell clearance mechanisms

Related keywords:

·Cellular aging
·Senescence pathway
·Senolytic research

② Longevity Research

FOXO4-DRI is commonly studied in areas including:

·Longevity mechanisms
·Age-related tissue changes
·Tissue function recovery models

Animal research areas include:

·Age-related functional decline
·Tissue repair capacity
·Changes in inflammatory markers

③ Tissue Function Research

Research areas include:

·Tissue regeneration
·Stem cell microenvironment regulation
·Chronic inflammation-related mechanisms

Q&A

Q: When can I receive the package?

A: It will be shipped as soon as possible after payment, and the shipping time is generally 7 to 15 days.

Q: What is the minimum amount I can order?

A: The minimum quantity we can order is 1 box, which contains 10 vials.

Q:How about the price? Can you make it cheaper?

A:We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.

Q: How do i keep the peptides when i receive it ?

A: Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

Company Profile

HKX is a reliable manufacturer and exporter of peptide raw materials.

We have strong R&D capabilities and advanced production facilities. Our products cover various synthetic peptides and related raw materials, which are widely used in scientific research and pharmaceutical development. Every batch of goods undergoes rigorous laboratory testing to meet international quality standards.

We have years of international trade experience and a complete logistics system. Neutral packaging is used for all goods to comply with international shipping regulations. We provide flexible order solutions for customers, from small trial orders to large bulk purchases.

We provide:

✔ High purity raw materials
✔ Strict quality inspection
✔ Competitive factory pricing
✔ Fast response service
✔ Global shipping support
✔ Professional after-sales service

Sticking to the philosophy of Quality Priority and Customer Oriented, we sincerely welcome customers from all over the world to negotiate business and create win-win cooperation.

Contact Us

Please contact us if you have any doubts regarding our products or enterprise.

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