Thymalin is a polypeptide complex isolated from the thymus and regulating the functions of the immune system. Thymalin is effective in therapy of acute respiratory syndrome, chronic obstructive bronchitis, and other immunopathology. Thymalin increases functional activity of T lymphocytes, but the targeted molecular mechanism of its biological activity requires further study. We studied the influence of thymalin on differentiation of human hematopoietic stem cells (HSC) and expression of CD28 molecule involved in the implementation of antiviral immunity in COVID-19 infection. It was found that thymalin reduced the expression of CD44 (stem cell marker) and CD117 (molecule of the intermediate stage of HSC differentiation) by 2-3 times and increased the expression of CD28 (marker of mature T lymphocytes) by 6.8 times. This indirectly indicates that thymalin stimulated differentiation of CD117+ cells into mature CD28+T lymphocytes. It is known that in patients with severe COVID-19, the number of CD28+, CD4+, CD8+T lymphocytes in the blood decreased, which attested to a pronounced suppression of immunity. It is possible that the antiviral effect of thymalin consists in compensatory stimulation of HSC differentiation into CD28+T lymphocytes at the stage of immunity suppression in unfavorable course of viral infection.
| Items | Specifications |
| Product | Peptides |
| Apperance | White Fine Powder |
| Purity | >99% |
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Our company is an R&D-oriented sales company. With its excellent quality and highly competitive prices, enjoy a very high reputation in China's sales industry. The company adheres to international standards such as ISO and provides customized services. Based on mass production, high-volume wholesale prices third-party testing, and certificate reports, our products provide high-quality products to numerous domestic and foreign enterprises. Our values are "integrity, pragmatism, innovation, and development We hope to cooperate with you with high-quality products and competitive prices. All products undergo strict quality inspection before leaving the factory, and ODM/OEM can be according to the needs of different customers. We are committed to providing you with the most competitive prices to ensure you stand out in the market, and we accept various payment methods. Our has a complete return and exchange policy. Special designs, special transportation channels, and free home delivery. Our products are exported to the United States, Australia, Canada, etc.
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