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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Imatinib for Sale > Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd
Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - large image1
Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - image1
Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - image2
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Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - image4
Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - image5
Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd buy - image6

Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd

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Unit Price:

$100-130/G FOB

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CAS No.:

152459-95-5

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Imatinib STI571; CGP57148B
    CAS Number 152459-95-5 152459-95-5 
    Molecular Formula C₂₉H₃₁N₇O — 
    Molecular Weight 493.60 g/mol — 
    Appearance Solid powder Visual inspection 
    Purity ≥98.0% Determined by HPLC 
    Melting Point 208 – 213°C — 
    Solubility DMSO: 3 mg/mL; H₂O: <1 mg/mL — 
    Storage 2-8°C, sealed, protect from moisture and light — 
    Packaging 1g, 5g, 10g, 25g, 100g Amber glass vials
    Application Research use only Oncology research, kinase inhibition studies


    —— Product Detail ——

    Product Overview

    • Imatinib (CAS 152459-95-5), also known as STI571 or CGP57148B, is a first-in-class small molecule tyrosine kinase inhibitor that revolutionized targeted cancer therapy . It appears as a solid powder with the molecular formula C₂₉H₃₁N₇O and a molecular weight of 493.60 g/mol


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Orange SolidImatinib is a kind of oral drugs used for the treatment of the chronic myelogenous leukemia (abbreviated CML) of positive symptoms of Philadelphia chromosome (Ber-Abl). It is suitable for being applied to adult patients in acute transformation phase, accelerated phase, and chronic phase with treatment failure with interferon. CML is a kind of hematopoietic stem cell disease caused by the DNA abnormalities in the bone marrow stem cells. DNA abnormalities will produce abnormal prote
    Solid
    Imatinib is a benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours. It has a role as an apoptosis inducer, a tyrosine kinase inhibitor and an antineoplastic agent. It is a N-methylpiperazine, a member of pyridines, a member of benzamides, an aromatic amine and a member of pyrimidines. It derives from a benzamide.|Imatinib is a small molecule kinase inhibitor used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN). It is occasionally referred to as CGP57148B or STI571 (especially in older publications). It is used in treating chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. It is the first member of a new class of agents that act by inhibiting particular tyrosine kinase enzymes, instead of non-specifically inhibiting rapidly dividing cells.|Imatinib is a Kinase Inhibitor. The mechanism of action of imatinib is as a Protein Kinase Inhibitor.|Imatinib is specific tyrosine kinase receptor inhibitor that is used in the therapy of Philadelphia chromosome-positive chronic myelogenous leukemia and gastrointestinal stromal tumors, both of which are marked by an abnormal, constitutively expressed tyrosine kinase that causes unregulated cell growth. Imatinib therapy is associated with transient elevations in serum aminotransferase levels and rare instances of clinically apparent acute liver injury which can be severe and sometimes fatal.|Imatinib is an antineoplastic agent that inhibits the Bcr-Abl fusion protein tyrosine kinase, an abnormal enzyme produced by chronic myeloid leukemia cells that contain the Philadelphia chromosome. Imatinib also inhibits the receptor tyrosine kinases for platelet-derived growth factor (PDGF) and stem cell factor (SCF)/c-kit; the SCF/c-kit receptor tyrosine kinase is activated in gastrointestinal stromal tumor (GIST). This agent inhibits proliferation and induces apoptosis in cells that overexpress these oncoproteins.|A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.

    Certificates
    • Imatinib CAS 152459-95-5 First-in-Class BCR-ABL Tyrosine Kinase Inhibitor for CML and GIST Research hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Imatinib

    Other Name:

    Benzamide,4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide;CGP 57148;Imatinib;4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide;Genfatinib;N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide

    CAS No.:

    152459-95-5

    Molecular Formula:

    C29H31N7O

    InChIKeys:

    InChIKey=KTUFNOKKBVMGRW-UHFFFAOYSA-N

    Molecular Weight:

    493.6

    Exact Mass:

    493.60

    EC Number:

    1308068-626-2

    UNII:

    BKJ8M8G5HI

    NSC Number:

    759854|743414

    DSSTox ID:

    DTXSID3037125

    NCI Thesaurus Code:

    C62035

    ATC Code:

    L01XE01|L - Antineoplastic and immunomodulating agents

    HScode:

    29339900

    Characteristics
    PSA:

    86.3

    XLogP3:

    3

    Appearance:

    Solid

    Density:

    1'+-.0.06 g/cm3(Predicted)

    Melting Point:

    208-209 °C @ Solvent: Dichloromethane, Hexane

    Boiling Point:

    754.9ºC at 760 mmHg

    Flash Point:

    410.3ºC

    Water Solubility:

    Very soluble in water at pH < 5.5 (mesylate salt)

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    6.03E-24mmHg at 25°C

    Collision Cross Section:

    214.6 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

    Hazard Identification

    Classification of the substance or mixture

    Germ cell mutagenicity, Category 2

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H341 Suspected of causing genetic defects

    H351 Suspected of causing cancer

    H360 May damage fertility or the unborn child

    H362 May cause harm to breast-fed children

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Imatinib

    100 G Oct 17, 2025
    Pakistan

    Imatinib

    1 KG Jul 23, 2025
    India

    Imatinib Methane Sulphate

    100 KG Jun 9, 2025
    Post an enquiry for this product
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