Bilobalide 98% Purity Ginkgo Terpene Lactone Standard CAS 33570-04-6 Research Grade Reference Standard

Product Overview

Bilobalide is a naturally occurring sesquiterpene lactone found in the leaves and roots of Ginkgo biloba. It is one of the characteristic terpene lactones in Ginkgo biloba extract and serves as an important reference standard for quality control of Ginkgo products.

With the molecular formula C₁₅H₁₈O₈ and a molecular weight of 326.30 g/mol, this compound appears as a white to off-white crystalline powder. It is soluble in methanol, ethanol, and DMSO. The product is supplied at ≥98% purity as determined by HPLC analysis.

Synthetic Process

Bilobalide is obtained through isolation from Ginkgo biloba leaves:

1. Extraction: Ginkgo leaves are extracted with aqueous acetone or ethanol.

2. Chromatographic Separation: The extract is fractionated using column chromatography.

3. Purification: Preparative HPLC or recrystallization yields the pure compound.

4. Identity Confirmation: Structure is confirmed by NMR and mass spectrometry.

Mechanism of Action & Applications

This compound is primarily used as:

• Reference Standard: For the quantification of terpene lactones in Ginkgo biloba extracts.

• Quality Control: Used in the quality assessment of Ginkgo products and dietary supplements.

• Pharmacological Research: Serves as a standard for bioavailability and metabolism studies.

• Natural Product Chemistry: Used as a reference for sesquiterpene lactone identification.

Quality Specifications

• Purity: ≥98.0% determined by HPLC.

• Identity: Confirmed by NMR and mass spectrometry.

• Loss on Drying: ≤1.0%.

• Each batch is accompanied by a comprehensive COA.

• Stable for 24 months when stored at 2-8°C in sealed containers, protected from light.

Packaging & Storage

• Standard packaging: 10mg, 20mg, 50mg amber glass vials.

• Store at 2-8°C, protected from light and moisture.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.