88 Factory supply Tropisetron hydrochloride CAS 105826-92-4 Bulk discount available Fast shipping to Australia available

White to Off-White Crystalline SolidChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Tropisetron hydrochloride is a hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride. It has a role as an anti-inflammatory agent, an antiemetic, an apoptosis inhibitor, an immunomodulator, a neuroprotective agent, a nicotinic acetylcholine receptor agonist, a serotonergic antagonist and a trypanocidal drug. It contains a tropisetron(1+).|Tropisetron Hydrochloride is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities. Tropisetron competitively binds to and blocks the action of serotonin at 5HT3 receptors peripherally on vagus nerve terminals located in the gastrointestinal (GI) tract as well as centrally in the chemoreceptor trigger zone (CTZ) of the area postrema of the central nervous system (CNS). This results in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.|An indole derivative and 5-HT3 RECEPTOR antagonist that is used for the prevention of nausea and vomiting.