Isorhamnetin 3-robinobioside 70% Purity Isorhamnetin 3-robinobioside 70% Purity Natural Product Reference Standard CAS Natural Product Reference Stan

• Product Overview

  Isorhamnetin 3-robinobioside is a naturally occurring flavonoid glycoside commonly found in various plant species including Ginkgo biloba, Hippophae rhamnoides, and Bupleurum species. It is composed of the flavonoid aglycone isorhamnetin (3'-methoxyquercetin) linked to a robinobioside sugar moiety at the 3-position. The compound exhibits a characteristic light yellow to pale yellow powder appearance with molecular formula C₂₈H₃₂O₁₆ and molecular weight of approximately 624.55 g/mol. This product is offered as a reference standard for phytochemical research and quality control applications.

  Biosynthetic Pathway & Natural Sources

  In plants, isorhamnetin 3-robinobioside is biosynthesized through the phenylpropanoid pathway. The aglycone isorhamnetin is derived from quercetin via methylation catalyzed by caffeoyl-CoA O-methyltransferase, followed by glycosylation at the 3-hydroxyl position with robinobiose (a disaccharide composed of rhamnose and galactose). Primary natural sources include sea buckthorn berries, ginkgo biloba leaves, and various medicinal herbs used in traditional medicine systems.

  Research Applications & Pharmacological Significance

  This flavonoid glycoside has garnered significant research interest due to its potential bioactivities:

  • Antioxidant Activity: Exhibits free radical scavenging properties through its phenolic hydroxyl groups, contributing to cellular protection against oxidative stress

  • Cardiovascular Research: Investigated for potential vasodilatory and cardioprotective effects

  • Anti-inflammatory Studies: Shows inhibitory activity against inflammatory mediators including COX-2 and pro-inflammatory cytokines

  • Quality Control Marker: Serves as a reference compound for HPLC fingerprinting and standardization of plant extracts, particularly in sea buckthorn and ginkgo products

  • Metabolite Studies: Useful in pharmacokinetic studies to track flavonoid absorption and metabolism

  Quality Specifications

  Our isorhamnetin 3-robinobioside is manufactured under strict quality control:

  • Purity: ≥70.0% determined by HPLC (area normalization)

  • Identification: Confirmed by UV-Vis and MS spectral matching

  • Appearance: Light yellow to yellow powder

  • Loss on Drying: ≤5.0%

  • Solubility: Soluble in DMSO, methanol, and aqueous ethanol

  • Each batch accompanied by Certificate of Analysis (COA)

  • Stable for 24 months when stored at 2-8°C in sealed containers protected from light

  Packaging & Shipping

  We offer flexible packaging options to meet diverse research needs:

  • Standard packaging: 20mg amber glass vial

  • Bulk quantities available upon request

  • Shipped at ambient temperature with moisture protection

  • International shipping available with proper documentation

  • Recommended storage: 2-8°C, protected from light and moisture

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.