Glutathione, Reduced glutathione, L-Glutathione, GSH

Description

Glutathione (reduced form, abbreviated as GSH) is a naturally occurring tripeptide in human cells. It is synthesized by the condensation of three amino acids: glutamic acid, cysteine and glycine. Its CAS number is 70-18-8, molecular formula C₁₀H₁₇N₃O₆S, and molecular weight 307.32. As one of the most important endogenous antioxidants in the human body, it plays a critical role in maintaining cellular redox balance and scavenging free radicals. This product is a high-purity (≥98%, tested by HPLC) white crystalline powder with good water solubility, and is widely used in scientific research experiments, dietary supplement raw materials and cosmetic raw materials.

Key Effects

Glutathione is known as the body's "antioxidant defense line", and its core function stems from the reactive thiol group (-SH) in its molecular structure. It can directly scavenge free radicals in the body, and acts as a substrate for multiple antioxidant enzymes, participating in cellular detoxification and the maintenance of redox balance. It is closely associated with studies on immune function, liver metabolism and skin condition, and ranks among the most well-recognized ingredients in the field of antioxidation.

Specifically, its functions demonstrated in scientific research and raw material applications include:
Antioxidation and free radical scavenging: As an endogenous antioxidant, it neutralizes free radicals directly and helps cells resist oxidative stress.
Detoxification: It can bind to various metabolic wastes and exogenous substances to assist the liver in detoxification.
Maintenance of redox balance: It regulates the intracellular redox state via the GSH/GSSG cycle.
Support for immune function: It provides a stable antioxidant environment for the normal operation of immune cells.
Skincare-related effects: In cosmetic research, it is linked to inhibiting melanin production and brightening skin tone, making it a popular active skincare ingredient.

Applications

Glutathione is applied in three major fields: scientific research, health products and cosmetics. In laboratories, it is a common reagent for oxidative stress research, cell culture and enzymology experiments. In the industrial sector, it serves as a well-established raw material for dietary supplements and brightening skincare cosmetics, enjoying high market recognition and stable demand.

Specific application scenarios include:
Scientific research experiments: Used in basic experiments such as oxidative stress research, cell culture and enzymatic reactions.
Raw material for dietary supplements: Applied in formula development of antioxidant health products.
Cosmetic raw material: Used in formulations of skin brightening and antioxidant skincare products.
Pharmaceutical intermediate: Serves as a raw material for the research and development of related drugs and preparations.
Detection and quality control: Employed in the development of GSH/GSSG content detection methods and quality control.