API Piroxicam Raw Material Powder CAS36322-90-4 Piroxicam
COA TDS 2 Inquiries
36322-90-4
Pharmaceutical Grade
99%
shenzhen
HS
25kg drum
Yes
2026-10-20
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferencePiroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.
Solid
Piroxicam is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. It has a role as an analgesic, a cyclooxygenase 1 inhibitor, a non-steroidal anti-inflammatory drug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and an antirheumatic drug. It is a benzothiazine, a member of pyridines and a monocarboxylic acid amide.|A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.|Piroxicam is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of piroxicam is as a Cyclooxygenase Inhibitor.|Piroxicam is a commonly used nonsteroidal antiinflammatory drug (NSAID) that is available by prescription only and is used in therapy of chronic arthritis. Piroxicam can cause mild serum aminotransferase elevations and, in rare instances, leads to clinically apparent acute liver injury that can be severe and even fatal.|Piroxicam is a nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. As a non-selective, nonsteroidal anti-inflammatory drug (NSAID), piroxicam binds and chelates both isoforms of cyclooxygenases (COX1 and COX2), thereby stalling phospholipase A2 activity and conversion of arachidonic acid into prostaglandin precursors at the rate limiting cyclooxygenase enzyme step. This results in inhibition of prostaglandin biosynthesis. As a second, independent effect, piroxicam inhibits the activation of neutrophils thereby contributing to its overall anti-inflammatory effects.CertificatesBasic Info-
Product Name:
Piroxicam
Other Name:2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-2-pyridinyl-,1,1-dioxide;Piroxicam;Pyroxycam;Baxo;Feldene;Piroftal;CHF 1251;Roxicam;4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;NSC 666076;Sasulen;Doblexan;Improntal;Piroflex;Bruxicam;Erazon;Flogobene;Geldene;Reudene;Artroxicam;Roxiden;Solocalm;Riacen;Larapam;Zunden;Caliment;Pirkam;CP 16171;Felden gel;Feldene Zydis;Dolibid;Feldene Melt;Felvin 20;Pixicam;Feloxin;Nkoyo piroxicam;Felxicam;Neoxicam;Uphaxicam;Maxvin;Laxidene;Rheugesic;Piroxidine;Dispercam;Murupe;Feledene;Feldoral;Piroxitas-DT;Nesprex-DT;Flogosan;Inflacin
CAS No.:36322-90-4
UN No.:2811
Molecular Formula:C15H13N3O4S
InChIKeys:InChIKey=QYSPLQLAKJAUJT-UHFFFAOYSA-N
Molecular Weight:331.34600
Exact Mass:331.35
EC Number:252-974-3
UNII:13T4O6VMAM
NSC Number:757284|666076
DSSTox ID:DTXSID5021170
NCI Thesaurus Code:C751
ATC Code:M01AC01|M - Musculo-skeletal system|S - Sensory organs
HScode:3005101000
Categories:
Characteristics-
PSA:
107.98000
XLogP3:3.1
Appearance:Off-white to pale yellow solid
Density:1.563 g/cm3
Melting Point:198-200 °C
Flash Point:297.6±32.9 °C
Refractive Index:1.714
Water Solubility:Soluble in water, ethanol, chloroform, ethyl acetate.
Storage Conditions:2-8ºC
Toxicity:LD50 orally in mice: 360 mg/kg (Wiseman)
Dissociation Constants:6.3
Collision Cross Section:170.9 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|170.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|170.9 Ų [M+H]+ [CCS Type: TW]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Spain
Piroxicam Crude
4500 KG Sep 20, 2026
Pakistan
Piroxicam
100 KG Jan 24, 2025 Post an enquiry for this product
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