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Competitive Price CAS 654671-77-9 Sitagliptin Phosphate Monohydrate From Direct Manufacturer

Name: Competitive Price CAS 654671-77-9 Sitagliptin Phosphate Monohydrate From Direct Manufacturer
Brand: guozhao
SKU: pr2609224392
Price: 50 USD
Availability: InStock

2 Inquiries

Unit Price:

$50-60/MT FOB

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CAS No.:

654671-77-9

Grade:

Industrial Grade

Content:

99%

Port:

qingdao

Brand:

guozhao

Packaging:

25kg/bag

Sample Available:

Yes

Price valid (until):

2026-11-10

Contact Supplier

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Shandong Guozhao Import and Export Co., Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

CHEMICALS

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Product Description
Seller Information
Inquiry History

Description

Product Description

Product Name:	Sitagliptin phosphate monohydrate
CAS:	654671-77-9
MF:	C16H18F6N5O5P
MW:	505.31
EINECS:	682-492-2
Fp	274.3ºC

Sitaglipti phosphate monohydrate is a selective and potent inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). It is primarily used in the management of type 2 diabetes mellitus. By inhibiting DPP-4, sitaglipti increases the levels of incretin hormones, which help regulate blood glucose levels. This results in enhanced insuli secretion and reduced glucagon release, contributing to improved glucose control. Sitaglipti phosphate monohydrate is the monohydrate form of sitaglipti phosphate, providing stability and ease of formulation in pharmaceutical preparations.

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FAQ

Q:What is your packing?
A: The products are usually packaged in bags, cartons and drums. Product packaging varies according to the product.We accept custom packaging.

Q:What is the delivery time?
A: Products are in stock. Shipping time depends on the type and quantity of the product. About 7-15days.

Q:What is the payment terms?
A: TT or spot letter of credit. The payment method is determined by negotiation.

Q:What is your transport?
A: Normally by sea ,by truck or by Rail;Urgently by air .

Q:Can I get the sample before placing the order?
A: Yes,Of course,click below "Send your message to this supplier"or contact us to get your FREE sample!

Q:Can you give me a discount?
A: Of course, we will offer you the best discount according to the quantity of your order.

Q:Where is your shipping port?
A: Qingdao port

Q:what can you buy from us?

A:Epoxy Resin,PVC Resin,Color Liquid Pigment,Color Powder,Oxide

Q:How about your after-sale service?
A:Any problems,we will try our bese to find the best solution

ECHEMI Editorial Reference

Sitagliptin phosphate monohydrate is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts
Sitagliptin Phosphate is the phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.|A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.

Basic Info

Product Name:

Sitagliptin phosphate monohydrate

Other Name:

1-Butanone,3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-,(3R)-,phosphate,hydrate (1:1:1);1,2,4-Triazolo[4,3-a]pyrazine,7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-,phosphate (1:1),monohydrate;(2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine dihydrogen phosphate monohydrate;Sitagliptin phosphate monohydrate;1253056-03-9

CAS No.:

654671-77-9

Molecular Formula:

C16H15F6N5O.H3O4P.H2O

InChIKeys:

InChIKey=GQPYTJVDPQTBQC-KLQYNRQASA-N

Molecular Weight:

523.3240802

Exact Mass:

523.105530

EC Number:

1806241-263-5

UNII:

TS63EW8X6F

NCI Thesaurus Code:

C73811

ATC Code:

A10BH01|A10BD24

HScode:

2933990090

Categories:

Inhibitor Drugs

Characteristics

PSA:

156

XLogP3:

1.66180

Appearance:

White or almost white crystalline powder

Boiling Point:

529.9ºC at 760 mmHg

Flash Point:

274.3℃

See More Sitagliptin phosphate monohydrate Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Sitagliptin phosphate monohydrate Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
CHEMICALS

Location:
No. 109, Chailu Street, Qingnian Park Subdistrict, Huaian District, Jinan City, Shandong Province 280

Year of Establishment:
2026

Shandong Guozhao Import and Export Co., Ltd., located at No. 280, Chalu Street, Qingnian Park Subdistrict, Huaiyin District, Jinan City, Shandong Province, primarily engages in import and export of goods; sales of chemical products (excluding licensed chemical products); sales of specialty chemical products (excluding hazardous chemicals); sales of plastic products; sales of metal products; sales of building materials; sales of architectural decoration materials; sales of daily-use chemical products; sales of food additives; sales of feed additives; sales of fertilizers; sales of batteries; and general cargo warehousing services (excluding items requiring licensing or approval, such as hazardous chemicals).

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	Sitagliptin phosphate 99%	50 KG	Nov 13, 2023
Egypt	Sitagliptin phosphate monohydrate	3.00 KG	Oct 11, 2023

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Competitive Price CAS 654671-77-9 Sitagliptin Phosphate Monohydrate From Direct Manufacturer

Product Description

Seller Information