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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Sitagliptin phosphate monohydrate for Sale > Sitagliptin phosphate monohydrate CAS 654671-77-9
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Sitagliptin phosphate monohydrate CAS 654671-77-9

2 Inquiries

Unit Price:

$10.2-11.22/G FOB

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CAS No.:

654671-77-9

Grade:

Chemical Grade

Content:

99%

Port:

shanghai

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2026-06-25

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Apigenin,PQQ,NMNH

  • Product Description

  • Seller Information

  • History Price

  • Inquiry History

  • Description
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    Q1: What's your MOQ?
    A:It depends on different products,we can accept sample order or provide free sample for your test.
    Q2:How about delivery leadtime?
    A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q3: Is there a discount?
    A:Different quantity has different discount.
    Q4:How to start orders or make payments?
    A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T or Bitcoin.
    Q5: How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q6:We don't know you at all, how can we trust you?
    A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
    Q7:Do you test all your goods before delivery?
    A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.

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    Description

    Name

    Sitagliptin phosphate monohydrate

    CAS number

    654671-77-9

    EINECS number

    682-492-2

    Synonym

    MK0431; MK 0431; MK-0431; sitagliptin phosphate; sitagliptin phosphate monohydrate; Sitagliptin phosphate hydrate

    Description

    Sitagliptin, also known as MK-0431, is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts. Sitagliptin is believed to exert its actions in patients with type 2 diabetes mellitus by slowing the inactivation of incretin hormones. By increasing and prolonging active incretin levels, sitagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner. Sitagliptin demonstrates selectivity for DPP-4 and does not inhibit DPP-8 or DPP-9 activity in vitro at concentrations approximating those from therapeutic doses.

    Structure

    \

    Molecular Formula

    C16H18F6N5O5P

    Molecular Weight

    505.31 g/mol

    Appearance

    Solid powder

    Quality Standard

    USP Standard

    Assay

    ≥98%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Store in cool place. Keep container tightly closed in a dry and well ventilated place.

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China

     

     

    Basic Info
    Product Name:

    Sitagliptin phosphate monohydrate

    Other Name:

    1-Butanone,3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-,(3R)-,phosphate,hydrate (1:1:1);1,2,4-Triazolo[4,3-a]pyrazine,7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-,phosphate (1:1),monohydrate;(2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine dihydrogen phosphate monohydrate;Sitagliptin phosphate monohydrate;1253056-03-9

    CAS No.:

    654671-77-9

    Molecular Formula:

    C16H15F6N5O.H3O4P.H2O

    InChIKeys:

    InChIKey=GQPYTJVDPQTBQC-KLQYNRQASA-N

    Molecular Weight:

    523.3240802

    Exact Mass:

    523.105530

    EC Number:

    1806241-263-5

    UNII:

    TS63EW8X6F

    NCI Thesaurus Code:

    C73811

    ATC Code:

    A10BH01|A10BD24

    HScode:

    2933990090

    Characteristics
    PSA:

    156

    XLogP3:

    1.66180

    Appearance:

    White or almost white crystalline powder

    Boiling Point:

    529.9ºC at 760 mmHg

    Flash Point:

    274.3℃

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Apigenin,PQQ,NMNH

    Location:

    Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2021

    Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Bangladesh

    Sitagliptin phosphate 99%

    50 KG Nov 13, 2023
    Egypt

    Sitagliptin phosphate monohydrate

    3.00 KG Oct 11, 2023
    Post an enquiry for this product
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