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Home > Organic Chemistry > Inorganic Acid Esters > Thionyl chloride for Sale > Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate
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Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate

11 Inquiries

Unit Price:

$150-170/G FOB

Get Latest Price
CAS No.:

7719-09-7

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

//

Packaging:

drum

Sample Available:

Yes

Price valid (until):

2026-10-23

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Shop Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate-Detailed Image 1

     Product Overview
    Thionyl chloride (SOCl₂) is a colorless to pale yellow fuming liquid with a pungent, suffocating odor. It is supplied at ≥99% purity and is widely used as a chlorinating agent in organic synthesis, particularly for converting carboxylic acids to acyl chlorides and alcohols to alkyl chlorides. It is also used in pharmaceutical manufacturing and as a dehydrating agent.

    Synthetic Process
    Thionyl chloride is produced industrially by the reaction of sulfur trioxide with sulfur dichloride or by the chlorination of sulfur dioxide. The crude product is purified by distillation to achieve ≥99% purity.

    Mechanism of Action
    As a chlorinating agent, thionyl chloride reacts with carboxylic acids to form acyl chlorides, releasing sulfur dioxide and hydrogen chloride as byproducts. It also converts alcohols to alkyl chlorides and sulfonic acids to sulfonyl chlorides. Its high reactivity and volatile byproducts make it a preferred reagent in organic synthesis.

    Quality Specifications

    • Assay: ≥99% (titration)

    • Appearance: colorless to pale yellow fuming liquid

    • Boiling point: 76°C

    • Density: 1.638 g/cm³ (20°C)

    • Reacts violently with water

    • Batch-specific Certificate of Analysis (COA)

    • GHS hazard: H300, H314, H318, H330

    Packaging & Storage
    Available in 25kg, 200kg drums and 1000kg IBC. Store in a cool, dry, well-ventilated area, away from water, moisture, bases, and alcohols. Keep container tightly closed and protected from light. Shelf life 12 months under proper storage.

    Parameter Specification Details
    Product Name Thionyl chloride Dichlorosulfoxide
    CAS Number 7719-09-7 —
    Molecular Formula SOCl₂ —
    Molecular Weight 118.97 —
    Category Inorganic Chemistry / Inorganic Acid Derivatives —
    Assay ≥99% Titration
    Appearance Colorless to pale yellow fuming liquid Pungent odor
    Boiling Point 76°C —
    Density 1.638 g/cm³ (20°C) —
    UN Number UN1836 Hazard Class 8
    Packaging 25kg, 200kg, 1000kg Drums / IBC
    Storage Cool, dry, away from water Sealed container
    Shelf Life 12 months Proper storage
    Application Chlorinating agent, pharmaceutical intermediate Industrial use
    Shop Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate-Detailed Image 2

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

    Shop Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate-Detailed Image 3
    Shop Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate-Detailed Image 4

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.

    ECHEMI Editorial Reference
    It is colorless or light yellow volatile liquid with a strong suffocating odor. It can also be miscible with benzene, chloroform and carbon tetrachloride. Colorless to slightly yellow liquid Thionyl chloride is a pale yellow to reddish liquid. Suffocating odor like sulfur dioxide. Fumes form when exposed to moist air.
    Thionyl chloride appears as a colorless to yellow fuming liquid with a suffocating pungent odor. Boiling point 79°C. A lachrymator. Highly corrosive and toxic. Long-term inhalation of low concentrations or short-term inhalation of high concentrations has adverse health effects.|DryPowder; Liquid|COLOURLESS-TO-YELLOW OR REDDISH FUMING LIQUID WITH PUNGENT ODOUR.|Colorless to yellow to reddish liquid with a pungent odor like sulfur dioxide.|Colorless to yellow to reddish liquid with a pungent odor like sulfur dioxide. [Note: Fumes form when exposed to moist air.]
    Thionyl chloride appears as a colorless to yellow fuming liquid with a suffocating pungent odor. Boiling point 79°C. A lachrymator. Highly corrosive and toxic. Long-term inhalation of low concentrations or short-term inhalation of high concentrations has adverse health effects.|Thionyl chloride is a sulfinyl halide in which both of the halide atoms are chorines. It is a sulfinyl halide and a chlorine molecular entity.
    Research & Reference Note

    Thionyl Chloride 99% Purity Chlorinating Agent CAS 7719-09-7 Industrial Grade Pharmaceutical Intermediate is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals

    Basic Info
    Product Name:

    Thionyl chloride

    Other Name:

    Thionyl chloride;Sulfurous oxychloride;Sulfurous dichloride;Sulfinyl chloride;Thionyl chloride (SOCl2);Sulfur chloride oxide (Cl2SO);Thionyl dichloride;Sulfur oxychloride (SOCl2);Sulfinyl dichloride;Sulfur oxychloride;Sulfur chloride oxide (SCl2O);2505209-14-1

    CAS No.:

    7719-09-7

    Molecular Formula:

    Cl2OS

    InChIKeys:

    InChIKey=FYSNRJHAOHDILO-UHFFFAOYSA-N

    Molecular Weight:

    118.97

    Exact Mass:

    118.97

    EC Number:

    231-748-8

    UNII:

    4A8YJA13N4

    ICSC Number:

    1409

    UN Number:

    1836

    DSSTox ID:

    DTXSID3064778

    Color/Form:

    Colorless to pale yellow or reddish liquid|Pale yellow to red liquid|Colorless to pale yellow, fuming, refractive liquid|Colorless to yellow to reddish liquid [Note: Fumes form when exposed to moist air]

    HScode:

    28121095

    Categories:

    Inorganic Acid Esters

    Characteristics
    PSA:

    36.3

    XLogP3:

    0.68

    Appearance:

    ≤50(APHA) Liquid

    Density:

    1.638 g/cm3 @ Temp: 20 °C

    Melting Point:

    -104.5 °C

    Boiling Point:

    76 °C @ Press: 760 Torr

    Flash Point:

    105°C

    Refractive Index:

    1.593

    Water Solubility:

    Solubility in water: reaction.;Miscible with toluene, chloroform, benzene, carbon tetrachloride and diethyl ether.

    Storage Conditions:

    Store at RT.

    Vapor Pressure:

    97 mm Hg ( 20 °C)

    Vapor Density:

    Relative vapour density (air = 1): 4.1

    Toxicity:

    Inhalation-Rat LC50: 500 PPM/1 hour

    Flammability characteristics:

    Irritating; emit toxic sulfur dioxide, hydrogen chloride, chlorine and other gases in water; decompose toxic sulfur oxides and chloride fumes when heated

    Explosive limit:

    Closed containers may rupture violently when heated.

    Odor:

    Suffocating odor

    Experimental Properties:

    Decomposes at 140 °C|Fuming, refractive liquid; decomposes when heated above 140 °C. Hydrolyzed by water forming sulfur dioxide and hydrochloric acid.|Specific heat of liquid: 1.00 J/g-K|Dielectric constant: 9.05 at 20 °C

    Air and Water Reactions:

    Emits dense corrosive fumes in moist air. Violently reacts with water to liberate hydrochloric acid and sulfur dioxide [NFPA 10th ed. 1991]. Thionyl chloride reacts vigorously with water to generate gaseous HCl and SO2. Based on a scenario where the chemical is spilled into an excess of water (at least 5 fold excess of water), half of the maximum theoretical yield of Sulfur Dioxide gas will be created in 0.25 minutes. Experimental details are in the following: "Development of the Table of Initial Isolation and Protective Distances for the 2008 Emergency Response Guidebook", ANL/DIS-09-2, D.F. Brown, H.M. Hartmann, W.A. Freeman, and W.D. Haney, Argonne National Laboratory, Argonne, Illinois, June 2009.

    Reactive Group:

    Acyl Halides, Sulfonyl Halides, and Chloroformates

    Reactivity Alerts:

    Water-Reactive

    Reactivity Profile:

    THIONYL CHLORIDE reacts, potentially explosively, with dimethyl sulfoxide or dimethylformamide containing traces of iron or zinc [Spitulnik, M. J., Chem. Eng. News, 1977, 55(31), p. 31]. Undergoes violent reactions with bases (ammonia, sodium hydroxide, potassium hydroxide, amines), alkali metals (sodium, potassium), esters (ethyl acetate), toluene mixed with ethanol / water [Bretherick, 5th ed., 1995, p. 1325]. Has an expansion ratio from gas to liquid of nearly 1000:1. Hence may cause an explosion if heated while contained [MCA Case History No. 1808]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Perchloric acid ignites on contact with sulfinyl chloride. (Bailar, 1973, Vol. 2, 1442). SOCl2 reacts with esters, such as ethyl acetate, forming toxic SO2 gas and water soluble/toxic acyl chlorides, catalyzed by Fe or Zn (Spagnuolo, C.J. et al. 1992. Chemical and Engineering News 70(22):2.).

    Flammable Limits:

    Noncombustible Liquid

    Physical Dangers:

    The vapour is heavier than air.

    Heat of Vaporization:

    31.0 kJ/mol

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin corrosion, Sub-category 1A

    Acute toxicity - Category 4, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H314 Causes severe skin burns and eye damage

    H332 Harmful if inhaled

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO contact with water. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Ventilation along the floor. Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    Colombia

    Thionyl chloride

    5 MT Jul 3, 2025
    Indonesia

    Thionyl chloride

    1 L Sep 16, 2026
    India

    Thionyl chloride

    5 KG Sep 4, 2025
    United Arab Emirates

    THIONYL CHLORIDE 98%

    2 KG Sep 25, 2024
    Indonesia

    Thionyl Chloride

    5 L Aug 11, 2026
    Russia

    Thionyl cloride

    143 KG Feb 26, 2026
    Morocco

    Thionyl Chloride (Chlorure de thionyle)

    100 MT Dec 9, 2025
    Morocco

    Thionyl chloride SOCl2

    1 MT Dec 3, 2025
    India

    Thionyl chloride

    20 MT Dec 31, 2024
    India

    thionyl chloride

    3 MT Aug 22, 2024
    Vietnam

    Thionyl Chloride

    1 MT Dec 12, 2023
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