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Home > Biochemical Engineering > Plant Extracts > Cycloastragenol for Sale > Cycloastragenol/telomerase activation, telomere elongation, antioxidant, anti-inflammatory, cardioprotective, anti-bone-loss
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Cycloastragenol/telomerase activation, telomere elongation, antioxidant, anti-inflammatory, cardioprotective, anti-bone-loss

3 Inquiries

Unit Price:

$100-130/G FOB

Get Latest Price
CAS No.:

78574-94-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

sinov

Packaging:

vial/box

Price valid (until):

2026-10-24

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Description

    This product is cycloastragenol, also known as astragaloside aglycone, with CAS number 78574-94-4. It is an active triterpenoid saponin component extracted and refined from the traditional Chinese medicinal herb Astragalus membranaceus, and also serves as the active metabolite of astragaloside IV, the main effective ingredient of astragalus. The molecular formula of the product is C₃₀H₅₀O₅, and its molecular weight is approximately 490.72. It normally appears as a white to off-white powder with a purity of over 98% (determined by HPLC). As a mature commercial plant extract raw material, this product can be supplied in various grades such as food grade, cosmetic grade and reagent grade according to application purposes. It is widely used in health food, cosmetics and scientific research fields, and is one of the natural ingredients that have attracted much attention in anti-aging research in recent years. The product should be stored in a sealed, light-proof, cool and dry place.

    Key Effects

    The most notable property of cycloastragenol is associated with "cellular lifespan". At the ends of chromosomes in human cells lies a structure called the "telomere", which gradually shortens with cell division and is regarded as one of the "biological clocks" of cellular senescence. Relevant studies indicate that cycloastragenol can activate a substance known as "telomerase" within cells, helping maintain telomere length, thereby demonstrating potential in research related to delaying cellular aging. In addition, it exhibits multiple biological activities including antioxidant effects, inflammation relief, cardiovascular protection and immune function support. It serves as a typical representative where active ingredients from traditional Chinese medicine intersect with modern anti-aging research.

    Its specific functions can be summarized as follows:
    Telomerase activation: Studies show it can activate telomerase to help preserve cellular telomere length, making it a well-known natural ingredient in the category of "telomerase activators";
    Antioxidation: Scavenges harmful free radicals in the body to protect cells and mitigate oxidative damage;
    Inflammation relief: Exerts a certain regulatory effect on inflammatory responses and helps maintain the stable state of the organism;
    Cardiovascular health support: Provides reference value for research on cardiovascular protection mechanisms;
    Immunomodulatory support: Plays an auxiliary role in regulating the immune function of the body;
    Active ingredient of traditional Chinese medicine: As a signature active ingredient of Astragalus membranaceus, it is used for research on the material basis of medicinal efficacy.

    Applications

    This product is a raw material derived from natural plant extracts. Its application scope covers multiple fields including health food, cosmetics and scientific research, with a particular focus on anti-aging applications, making it one of the varieties that attract high attention in export markets.

    Its main application areas can be summarized as follows:
    Health food and dietary supplements: Used as an active raw material for anti-aging and immune-enhancing products such as capsules and tablets;
    Anti-aging research: Serves as a key natural compound in research on telomerase and cellular senescence;
    Cosmetics industry: Incorporated into formulations of anti-aging, firming and repairing products such as serums and creams;
    Traditional Chinese medicine research and testing: Used as a standard reference substance for the quality control of preparations related to Astragalus membranaceus;
    Supply of scientific research reagents: Provided to universities, research institutes and pharmaceutical laboratories as experimental materials for natural product research;
    Export trade and raw material supply: Supplied as a natural extract raw material to health food manufacturers, cosmetic factories, scientific research institutions and traders, with specifications available upon customer request.

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    Items Specifications
    Cycloastragenol 10mg
    Cycloastragenol 1g
    Cycloastragenol 1kg
    ECHEMI Editorial Reference
    Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus (Fisch.) Bunge[1].Astramembrangenin is orally safe and has broad Extensive pharmacological effects, including telomerase activation, telomere elongation, anti-inflammatory and anti-oxidative properties[2].Astramembrangenin has antiaging properties, CAG stimulates telomerase activity in human neonatal keratinocytes and rat neuronal cells,
    Cycloastragenol is a sapogenin that is the aglycone derivative of astragaloside IV, a major saponin extracted from the root of Astragalus membranaceus. It has a role as a metabolite. It is a sapogenin, a pentacyclic triterpenoid, a tetrol and a member of oxolanes. It derives from a hydride of a 5alpha-gonane.

    Basic Info
    Product Name:

    Cycloastragenol

    Other Name:

    9,19-Cyclolanostane-3,6,16,25-tetrol,20,24-epoxy-,(3β,6α,16β,20R,24S)-;(3β,6α,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclosiversigenin;Astramembrangenin;Cycloastragenol;Cyclosieversigenin;Cyloastragenol;89396-45-2

    CAS No.:

    78574-94-4

    Molecular Formula:

    C30H50O5

    InChIKeys:

    InChIKey=WENNXORDXYGDTP-UOUCMYEWSA-N

    Molecular Weight:

    490.72

    Exact Mass:

    490.71

    UNII:

    X37D9F2L0V

    HScode:

    2942000000

    Categories:

    Plant Extracts

    Characteristics
    PSA:

    90.2

    XLogP3:

    4.4

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    239-241 °C @ Solvent: Methanol

    Boiling Point:

    617.2±55.0°C at 760 mmHg

    Flash Point:

    327.1±31.5 °C

    Refractive Index:

    1.582

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    High Purity Cycloastragenol CAS 78574-94-4

    1 KG Oct 14, 2025
    United States

    Cycloastragenol (synthetic)

    5 KG Sep 16, 2025
    Uzbekistan

    98% Cycloastragenol

    100 G Dec 3, 2025
    Post an enquiry for this product
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