Product Overview

6-Bromohexanoic acid is an organic compound with the molecular formula C₆H₁₁BrO₂ and molecular weight of 195.06 g/mol. This white to off-white crystalline solid is a valuable intermediate in pharmaceutical, agrochemical, and organic synthesis research. The compound features a bromine atom at the 6-position and a carboxylic acid group.

Synthetic Process

• Bromination: 6-Hydroxyhexanoic acid is brominated using hydrobromic acid or phosphorus tribromide

• Ring Opening: Caprolactone is reacted with hydrobromic acid to yield 6-bromohexanoic acid

• Purification: The crude product is purified by recrystallization from suitable solvents

• Drying: The purified product is dried under vacuum

Mechanism of Action

• Alkyl Bromide Reactivity: The bromine atom enables nucleophilic substitution reactions

• Carboxylic Acid Reactivity: The acid group can be converted to esters, amides, and acid chlorides

• Polymer Building Block: Used as a monomer for the preparation of functional polymers

Research Applications & Market Significance

• Pharmaceutical Research: Building block for drug discovery programs

• Organic Synthesis: Versatile intermediate for functionalized carboxylic acid derivatives

• Agrochemical Synthesis: Intermediate for pesticide development

• Material Science: Used in the preparation of specialty polymers and functional materials

Quality Specifications

• Purity: ≥98.0% determined by GC

• Melting point: 38-41°C

• Boiling point: 165-167°C (15 mmHg)

• Loss on drying: ≤0.5%

• Storage: 2-8°C, sealed, protected from light

• Stable for 24 months when properly stored

Packaging & Shipping

• Research quantities: 25g, 100g amber glass bottles

• Bulk quantities: 500g, 1kg amber glass bottles

• Shipped at ambient temperature