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Home > Biochemical Engineering > Polypeptide > Exendin-4 for Sale > Dependable polypeptide goods for laboratory, high assay, flexible packing selections
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Dependable polypeptide goods for laboratory, high assay, flexible packing selections

4 Inquiries

Unit Price:

$53/UNIT EXW

Get Latest Price
CAS No.:

141758-74-9

Grade:

Research Grade

Content:

99%

Port:

qingdao

Packaging:

5mg;10mg;15mg;20mg;30mg;40mg;50mg;100mg;500mg

Price valid (until):

2027-02-28

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Cosmetics

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Company Profile

    Our enterprise focuses on developing and supplying synthetic peptide raw materials for life science laboratory research. We have built standardized production workflows and assembled an experienced technical and sales team. We can tailor raw material solutions according to each lab’s experimental design, serving researchers across multiple regions worldwide.

    We uphold integrity and consistent product performance as our core principles. We keep track of evolving needs within the research community and adjust our inventory and supply plans accordingly. From initial consultation and order confirmation through production scheduling and dispatch, we aim to deliver streamlined service for every submission.

    Product Details

    This product line comprises research-grade synthetic peptide lyophilized powder, manufactured via chemical synthesis followed by freeze-drying processing. The lyophilization process lowers moisture levels, slows molecular degradation, and helps preserve material stability over storage.

    Each batch features fine, homogeneous powder that dissolves readily in compatible solvents, with low impurity profiles and consistent performance across production runs. It serves as a reliable material for biochemical assays, in vitro experiments and academic research projects.

    We support small trial batches as well as large-volume orders. Unit pricing becomes more competitive for larger quantities. Custom packaging arrangements can also be discussed to accommodate different laboratory operational preferences.

    Product Consistency

    We maintain careful oversight throughout the whole production workflow. Starting materials are sourced from qualified suppliers and reviewed before entering production.

    Synthesis and purification follow established operating procedures. Finished materials undergo multiple analytical assessments to confirm purity, moisture content and impurity profiles.

    Materials are cleared for dispatch once evaluation criteria are met. Batch records are retained, and relevant supporting documentation can be shared to support your research records upon request.

    Packaging and Logistics

    Our inner packaging uses professional light-blocking sealed vials. Outer packaging includes protective cushioning to reduce mechanical shock and temperature variation risks during transit.

    We work with trusted international logistics partners. Shipment will be arranged within 1–2 business days after payment confirmation, and a tracking number will be provided for shipment monitoring.

    Support Services

    Our sales and technical team provides dedicated support for laboratory buyers and responds to inquiries within 24 business hours.

    You may reach out for guidance on product selection, storage recommendations, order updates or packaging preferences. Custom labeling and repackaging options can be explored where feasible.

    After shipment, we continue tracking delivery progress. Please contact us promptly if any issues arise upon receipt, and we will work toward a suitable resolution.

    Storage Conditions

    Store in a cool, dry, dark, low-temperature environment. Avoid repeated freeze-thaw cycles. We recommend aliquoting materials based on experimental usage to help maintain sample integrity.

    Important Disclaimer

    This product is intended exclusively for in vitro laboratory research. It may NOT be used for human, clinical, diagnostic, medical, cosmetic, food or feed applications. The purchaser shall bear responsibility to ensure the product is used solely within permitted laboratory research scope.

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    Items Specifications
    Product type Synthetic peptide
    Grade Research grade
    Purity ≥99%
    Appearance White / off‑white lyophilized powder
    Package form Sealed glass vials
    Available experimental sizes 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 100 mg, 500 mg
    Minimum order 1 kit (10 vials)
    ECHEMI Editorial Reference
    Exendin-4 is a 39 amino acid polypeptide and incretin mimetic involved in the glucose-dependent enhancement of insulin secretion. It was first isolated from Gila monster saliva. It also promotes the reduction of hyperglycemia, glucose-dependent suppression of inappropriately high glucagon secretion, slowing of gastric emptying, and reduction of food intake, often with body weight reduction or blunting of weight gain. The synthetic form, Exenatide, is a glucagon-like peptide-1 (GLP-1) agonist approved for the treatment of diabetes mellitus type II, has a long half-life.

    Exenatide is the first drug in a new class of anti-diabetics known as the incretin mimetics, and it is indicated as adjunctive therapy to improve glycemic control in patients with type 2 diabetes who are taking metformin, a sulfonylurea, or both, but have not achieved adequate glycemic control. Exenatide is a functional analog of the human incretin Glucagon-Like Peptide-1 (GLP-1). GLP-1 is naturally released from cells in the GI tract in response to food intake and acts on its receptor on b-cells to potentiate glucose-stimulated insulin secretion. Exenatide is a long-acting agonist at the GLP-1 receptor. It is a synthetic version of a 39-amino acid peptide found in the salivary secretions of the Gila monster lizard.also moderates peak serum glucagon levels during hyperglycemic periods following meals, but does not interfere with glucagon release in response to hypoglycemia. 


    ChEBI: A bioactive polypeptide of 39 amino acid residues isolated from the saliva of the Gila monster (Heloderma suspectum). High-affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); potently indu es cAMP formation without stimulating amylase release in pancreatic acini; potentiates glucose-induced insulin secretion in isolated rat islets; protects against glutamate-induced neurotoxicity. A synthetic version is called exenatide.
    Exendin-4 is an incretin mimetic peptide, which is composed of 39 amino acids. It is an analog of glucagon-like peptide 1 (GLP-1), and an insulinotropic agent, with a long half-life. Exendin-4 was historically isolated from the venom of Gila monster lizard calledHeloderma suspectum.
    Exendin-4 Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 39 amino acids and having a molecular mass of approximately 4.2kDa. Exendin-4 is purified by proprietary chromatographic techniques.

    Basic Info
    Product Name:

    Exendin-4

    Other Name:

    HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2;Exenatide (Exendin-4);Exenatide free base;XENDIN-4;EXENDIN-4;M.W. 4186.61 C184H282N50O60S;HIS-GLY-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;HIS-GLY-GLU-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

    CAS No.:

    141758-74-9

    Molecular Formula:

    C184H282N50O60S

    InChIKeys:

    HTQBXNHDCUEHJF-AAPNSGCPNA-N

    Molecular Weight:

    4186.57188

    EC Number:

    686-356-3

    Color/Form:

    White to off-white

    HScode:

    2933290000

    Categories:

    Polypeptide

    Characteristics
    Water Solubility:

    Soluble in water (1 mg/ml)

    Critical Temperature & Pressure:

    −20°C

    Research
    Class:

    GLP-1 receptor agonist (exendin-based, 39-amino-acid peptide)

    Status:

    FDA-approved (Byetta 2005, Bydureon 2012)

    Mechanism:

    A synthetic 39-amino-acid peptide (exendin-4) that acts as a GLP-1 receptor agonist. It is not a GLP-1 analog but shares 53% sequence homology with human GLP-1. Exenatide enhances glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and reduces food intake. Bydureon is the extended-release formulation.

    EC50 (GLP1R Ic50):

    3.22 nM

    Source:

    Exendin-4 binding data: Eng J, et al. J Biol Chem. 1992;267(11):7402-7405. DrugBank: DB01276.DOI

    Clinical Development:

    NCT00053397

    FDA:

    Byetta, Bydureon BCise (approved 2005-04-28)

    References
    ChEMBL:

    CHEMBL486

    DrugBank:

    DB01276

    KEGG DRUG:

    D04104

    PubChem:

    PubChem

    Disclaimer:

    Exenatide is FDA-approved as a prescription medicine (Byetta, Bydureon) for type 2 diabetes. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Cosmetics

    Location:

    Room 204, Unit 1, Building 3, Liming 1st District, Choujiang Subdistrict, Wenwu City, Jinhua City, China (Zhejiang) Pilot Free Trade Zone

    Year of Establishment:

    2026

  • Inquiry History
    4 Inquiries
    Country Product Purchase Quantity Date Posted
    Philippines

    Exenatide (CAS: 141758-74-9)

    10 G Sep 19, 2026
    Philippines

    Exenatide

    10 G Aug 13, 2026
    Philippines

    Exenatide

    10 G Sep 16, 2026
    United States

    Exenatide

    5  Mar 11, 2026
    Post an enquiry for this product
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