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Home > Encyclopedia > 1-Methyl-1,2,3,4-tetrahydroisoquinoline

1-Methyl-1,2,3,4-tetrahydroisoquinoline

1-Methyl-1,2,3,4-tetrahydroisoquinoline structure

1-Methyl-1,2,3,4-tetrahydroisoquinoline 

structure
  • CAS No:

    4965-09-7

  • Formula:

    C10H13N

  • Chemical Name:

    1-Methyl-1,2,3,4-tetrahydroisoquinoline

  • Synonyms:

    Isoquinoline,1,2,3,4-tetrahydro-1-methyl-;1,2,3,4-Tetrahydro-1-methylisoquinoline;1-Methyl-1,2,3,4-tetrahydroisoquinoline;90192-87-3

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

Colorless to pale yellow liquid


1-methyl-1,2,3,4-tetrahydroisoquinoline is a member of isoquinolines.

1-Methyl-1,2,3,4-tetrahydroisoquinoline Basic Attributes

147.22

147.22

1533716-785-6

2933990090

Characteristics

12

1.7

Pale yellow Liquid

1.0±0.1 g/cm3

119℃/18mm

100.0±14.2 °C

1.5570 to 1.5610

Slightly soluble in water.

2-8°C

Safety Information

NONH for all modes of transport

NX5087850

P261-P305 + P351 + P338

H302-H315-H319-H335

|Warning|H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)

1-M-THIQ

Computed Properties

Molecular Weight:147.22
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:147.104799419
Monoisotopic Mass:147.104799419
Topological Polar Surface Area:12
Heavy Atom Count:11
Complexity:133
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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