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TOSUFLOXACIN TOSILATE

TOSUFLOXACIN TOSILATE structure

CAS No:
100490-36-6
Formula:
C19H15F3N4O3
Chemical Name:
TOSUFLOXACIN TOSILATE
Synonyms:
1,8-naphthyridine-3-carboxylicacid,1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(;4-difluorophenyl)-6-fluoro-4-oxo-;a61827;a67107;1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-aminopyrrolidin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid;1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- (9CI);A-60969;Ozex
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively. It is a 1,8-naphthyridine derivative, an amino acid, a monocarboxylic acid, an organofluorine compound, an aminopyrrolidine, a tertiary amino compound, a primary amino compound and a quinolone antibiotic. It is a conjugate base of a 1-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]pyrrolidin-3-aminium.

TOSUFLOXACIN TOSILATE Basic Attributes

Molecular Weight：

404.34

Exact Mass：

404.34

DSSTox ID：

DTXSID2044135

ATC Code：

J - Antiinfectives for systemic use

Characteristics

PSA：

99.8

XLogP3：

2.80390

Appearance：

White powder

Density：

1.558±0.06 g/cm3(Predicted)

Boiling Point：

614.4±55.0 °C(Predicted)

Flash Point：

325.4ºC

Vapor Pressure：

5.96E-16mmHg at 25°C

PKA：

5.79±0.70(Predicted)

Safety Information

wgk germany：

hazard class code：

R36/37/38:Irritating to eyes, respiratory system and skin .

safety instructions：

S26-S37/39

Marks：

Drug Information

MeSH Entry Terms：

7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

TOSUFLOXACIN TOSILATE Use and Manufacturing

It has broad-spectrum antibacterial activity. It has strong antibacterial activity against Gram-positive bacteria including Staphylococcus aureus, Staphylococcus aureus, S. pyogenes, and Streptococcus pneumoniae. It is very strong against Gram-negative bacteria including Pseudomonas aeruginosa and anaerobic bacteria. Antibacterial activity and bactericidal effect. For respiratory tract infections, soft tissue injuries, pneumonia, urinary tract infections, gynecological infections, oral and ENT infections.

Tosufloxacin Tosilate (CAS# 100490-36-6) was identified in a Haemophilus influenza clone ST422.

Computed Properties

Molecular Weight:404.3
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:3
Exact Mass:404.10962484
Monoisotopic Mass:404.10962484
Topological Polar Surface Area:99.8
Heavy Atom Count:29
Complexity:708
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Glycine

Recommended Suppliers of TOSUFLOXACIN TOSILATE

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Tosufloxacin tosilate

CAS No.: 100490-36-6

Content: 99.00%

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Tosufloxacin cas 100490-36-6

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CAS No.: 100490-36-6

Grade: Pharmaceutical Grade

Content: 99%

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Guide of TOSUFLOXACIN TOSILATE

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Material
Recommended Suppliers
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TOSUFLOXACIN TOSILATE

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