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Home > Encyclopedia > L-NORADRENALINE BITARTRATE

L-NORADRENALINE BITARTRATE

pharmaceutical raw materials
L-NORADRENALINE BITARTRATE structure

L-NORADRENALINE BITARTRATE 

structure
  • CAS No:

    108341-18-0

  • Formula:

    C12H17NO9

  • Chemical Name:

    L-NORADRENALINE BITARTRATE

  • Synonyms:

    L-Arterenol hydrogen L-tartrate;L-Norepinephrine bitartrate salt;L-(-)-Norepinephrine (bitartrate hydrate);Levarterenol bitartrate monohydrate;4-[(1R)-2-amino-1-hydroxyethyl]-1,2-Benzenediol (2R,3R)-2,3-dihydroxybutanedioate hydrate (1:1:1);L-NORADRENALINE BITARTRATE;L-(-)-NOREPINEPHRINE-(+)-BITARTRATE;L-NOREPINEPHRINE BITARTRATE

  • Categories:

    Active Pharmaceutical Ingredients  >  Circulatory System Drugs

Description

White Solid


Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine bitartrate acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action.

L-NORADRENALINE BITARTRATE Basic Attributes

319.26

337.100896

1806241-263-5

IFY5PE3ZRW

DTXSID50148507

C48646

2937901500

Characteristics

201.77000

white

100-104 °C(lit.)

442.6ºC at 760mmHg

221.5ºC

-11 ° (C=5, H2O)

H2O: soluble50mg/mL, clear

Refrigerator

Safety Information

III

6.1

UN 2811 6.1/PG 2

3

26/27/28-28

22-26-36/37/39-45-36/37-28

DN6750000

T+

Missing Phrase - N15.00950417-P260-P262-P280-P302 + P352 + P310-P304 + P340 + P310

H300 + H310 + H330

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.|Danger|H300 (90.91%): Fatal if swallowed [Danger Acute toxicity, oral]|P260, P262, P264, P270, P271, P280, P284, P301+P310, P302+P350, P304+P340, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

L-NORADRENALINE BITARTRATE Use and Manufacturing

Demethylated precursor of epinephrine (adrenaline).It is a sympathomimetic hormone produced by the adrenal gland.

Computed Properties

Molecular Weight:337.28
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:5
Exact Mass:337.10089580
Monoisotopic Mass:337.10089580
Topological Polar Surface Area:203
Heavy Atom Count:23
Complexity:276
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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