Gemifioxacin mesylate
-
Gemifioxacin mesylate
structure -
-
CAS No:
210353-53-0
-
Formula:
C18H20FN5O4.CH4O3S
-
Chemical Name:
Gemifioxacin mesylate
-
Synonyms:
GEMIFIOXACIN MESYLATE;7-(3-aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid mesylate;LB-20304 Mesilate;Gemifioxacin mesylate, 98.5%;CS-775;(Z)-Gemifloxacin Mesilate;LB-20304a;SB-265805S
-
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs
-
CAS No:
Description
Gemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.
Gemifloxacin is a new fluoroquinolone derivative that is active against both Grampositive and Gram-negative bacteria, and it was launched as an oral treatment for bacterial respiratory infections. Compared with other fluoroquinolones currently on the market, gemifloxacin possesses enhanced in vitro activity against Streptococcus pneumoniae, including isolates resistant to b-lactams, macrolides, and ciprofloxacin. Gemifloxacin is specifically indicated for treating community- acquired pneumonia (CAP) caused by multi-drug resistant S. pneumoniae and for treating acute bacterial exacerbations of chronic bronchitis (AECB). The recommended dose of gemifloxacin is 320 mg daily for 5 days for AECB and 320 mg daily for 7 days for CAP.
gemifloxacin mesylate is a synthetic broad-spectrum antibacterial agent for oral administration. Gemifloxacin, a compound related to the fluoroquinolone class of antibiotics, is available as the mesylate salt in the sesquihydrate form. The mesylate salt is a white to light brown solid with a molecular weight of 485.49. Gemifloxacin is considered freely soluble at neutral pH (350 μg/mL at 37oC, pH 7.0).
ChEBI: Gemifloxacin mesylate is the mesylate salt of gemifloxacin. It has a role as an antimicrobial agent and a topoisomerase IV inhibitor. It contains a gemifloxacin.
Gemifioxacin mesylate Basic Attributes
485.49
485.138031
1312995-182-4
white to light brown
29339900
Characteristics
184
2.31610
beige solid
235-2370C
638.9°C at 760 mmHg
340.2ºC
H2O: 10mg/mL, clear
-20°C Freezer
room temp
Computed Properties
Molecular Weight:485.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:5
Exact Mass:485.13804746
Monoisotopic Mass:485.13804746
Topological Polar Surface Area:184
Heavy Atom Count:33
Complexity:817
Undefined Atom Stereocenter Count:1
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Unspecified
Recommended Suppliers of Gemifioxacin mesylate
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive
Learn More Other Chemicals
-
Benzyl oxopropyl mesylate
98518-10-6
-
Isoetharine mesylate
7279-75-6
-
Danofloxacin-d3 Mesylate
1217860-94-0
-
Des[3-[[(1-CarboxyMethyl)cyclopropyl]Methyl]thio]-2-propenyl Montelukast Mesylate Formula
1187586-82-8
-
Bitolterol mesylate Formula
30392-41-7
-
Casopitant mesylate Formula
414910-30-8
-
Safinamide mesylate Structure
202825-46-5
-
5-Chloro Bifeprunox Mesylate Structure
1217042-05-1
-
What is Camostat mesylate
59721-29-8
-
What is Pralidoxime mesylate
154-97-2