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Pralidoxime mesylate

Pralidoxime mesylate structure

CAS No:
154-97-2
Formula:
C7H9N2O.CH3O3S
Chemical Name:
Pralidoxime mesylate
Synonyms:
Pyridinium,2-[(hydroxyimino)methyl]-1-methyl-,methanesulfonate (1:1);Pyridinium,2-formyl-1-methyl-,methanesulfonate,oxime;Pyridinium,2-[(hydroxyimino)methyl]-1-methyl-,methanesulfonate (salt);2-Formyl-1-methylpyridinium methanesulfonate,oxime;2-(Hydroxyiminomethyl)-N-methylpyridinium methanesulfonate;2-(Hydroxyiminomethyl)-1-methylpyridinium methanesulfonate;P2S;1-Methyl-2-(hydroxyiminomethyl)pyridinium methanesulfonate;N-Methylpyridinium-2-aldoxime methanesulfonate;Pralidoxime mesylate;Pralidoxime methanesulfonate;Pralidoxime methosulfate;1-Methylpyridinium-2-aldoxime methanesulfonate;2-PAM methanesulfonate;2-Pyridinealdoxime methyl methanesulfonate;Contrathion;N-Methyl-2-pyridinaldoxime methanesulfonate;51729-73-8;857212-20-5
Categories:
Organic Chemistry > Amides

Description

Pralidoxime mesylate is a pyridinium salt and a methanesulfonate salt. It has a role as a cholinesterase reactivator and a cholinergic drug. It contains a pralidoxime.

Pralidoxime mesylate Basic Attributes

Molecular Weight：

232.25700

Exact Mass：

232.05200

EC Number：

205-839-8

UNII：

45CO7XIN2K

Characteristics

PSA：

102.05000

XLogP3：

0.56140

Melting Point：

236.5 °C

Boiling Point：

189.7ºC at 760mmHg

Flash Point：

68.5ºC

Drug Information

MeSH：

Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)|Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates. (See all compounds classified as Cholinesterase Reactivators.)

MeSH Entry Terms：

1-methylpyridinium-2-aldoxime ion

Computed Properties

Molecular Weight:232.26
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:232.05177804
Monoisotopic Mass:232.05177804
Topological Polar Surface Area:102
Heavy Atom Count:15
Complexity:204
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes