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Glibornuride

Glibornuride structure

CAS No:
26944-48-9
Formula:
C18H26N2O4S
Chemical Name:
Glibornuride
Synonyms:
Benzenesulfonamide,N-[[[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methyl-;Urea,1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)-,(1R,2R,3S,4S)-;Benzenesulfonamide,N-[[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methyl-,[1S-(endo,endo)]-;N-[[[(1S,2S,3R,4R)-3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methylbenzenesulfonamide;Glibornuride;endo,endo-1-[(1R)-(2-Hydroxy-3-bornyl)]-3-(p-tolylsulfonyl)urea;Ro 6-4563;Ro 6-4563/8;endo,endo-1-(2-Hydroxy-3-bornyl)-3-(p-tolylsulfonyl)urea;Glutril;Gluboride;24266-65-7
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

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Glibornuride Basic Attributes

Molecular Weight：

366.47504

Exact Mass：

366.48

EC Number：

248-124-6

Characteristics

PSA：

104

XLogP3：

3.84460

Density：

1.3g/cm3

Melting Point：

192-195 °C

Refractive Index：

1.6

Specific rotation：

D +63.8° (ethanol)

Glibornuride Use and Manufacturing

Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.