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Amifloxacin

Amifloxacin structure

CAS No:
86393-37-5
Formula:
C16H19FN4O3
Chemical Name:
Amifloxacin
Synonyms:
3-Quinolinecarboxylic acid,6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-;6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;Win 49375;Amifloxacin
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

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Description

Win49375 is a synthetic antibacterial agent of the quinolone class.

Solid

Amifloxacin is a member of quinolines.

Amifloxacin Basic Attributes

Molecular Weight：

334.349

Exact Mass：

334.35

EC Number：

289-231-8

UNII：

5TU5227KYQ

DSSTox ID：

DTXSID20235519

Characteristics

PSA：

76.1

XLogP3：

0.23

Appearance：

Solid

Density：

1.44g/cm3

Melting Point：

300 °C (decomp)

Boiling Point：

532.5ºC at 760mmHg

Flash Point：

275.8ºC

Refractive Index：

1.662

Drug Information

MeSH：

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)|Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)

MeSH Entry Terms：

6-fluoro-1-methylamino-7-(4-methylpiperazin-1-yl)-1,4-dihydroquinolin-4-one-3-carboxylic acid

Amifloxacin Use and Manufacturing

Antibacterial.

Computed Properties

Molecular Weight:334.35
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:334.14411864
Monoisotopic Mass:334.14411864
Topological Polar Surface Area:76.1
Heavy Atom Count:24
Complexity:547
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes