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Norvoncomycin hydrochloride

Norvoncomycin hydrochloride structure

CAS No:
213997-73-0
Formula:
C65H74Cl3N9O24
Chemical Name:
Norvoncomycin hydrochloride
Synonyms:
Norvoncomycin hydrochloride;Norvancomycin hydrochloride
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Norvancomycin hydrochloride is applicable for endocarditis, osteomyelitis, pneumonia, sepsis or soft tissue infections causedby Staphylococcus (including Methicillin-resistant strains and multidrug-resistant microbial strains).Target: Antibacterial

Norvoncomycin hydrochloride Basic Attributes

Molecular Weight：

1471.68796

Exact Mass：

1469.391235

EC Number：

1308068-626-2

Characteristics

PSA：

545

Norvoncomycin hydrochloride Use and Manufacturing

It belongs to antibiotics and is used to treat penicillin-resistant Staphylococcus and other infections

Computed Properties

Molecular Weight:1471.7
Hydrogen Bond Donor Count:20
Hydrogen Bond Acceptor Count:26
Rotatable Bond Count:12
Exact Mass:1469.391227
Monoisotopic Mass:1469.391227
Topological Polar Surface Area:545
Heavy Atom Count:101
Complexity:2940
Defined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It has good antibacterial effect on most Gram-positive bacteria such as Staphylococcus aureus and methicillin-sensitive and -resistant strains of coagulase-negative Staphylococci, various streptococci, Streptococcus pneumoniae and Enterococcus.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Norvancomycin Hydrochloride for Injection
Ingredients	Norvancomycin hydrochloride.
Indication	1. The combination or sequential application of aminoglycosides, amphotericin B injection, aspirin, other salicylates, bacitracin (injection), bumetanide injection, capreomycin, carmustine, cisplatin, cyclosporine, ethacrynic acid injection, furosemide injection, streptozotocin, paromomycin and polymyxins with norvancomycin may increase the potential for ototoxicity and/or nephrotoxicity; hearing loss may occur, and may continue to progress to deafness even after drug discontinuation. The reaction may be reversible, but often becomes permanent. Hearing must be monitored when this product is used in combination or sequentially with other deafness-causing antibacterial drugs. Since norvancomycin is often used in combination with aminoglycosides for the treatment of bacterial endocarditis and streptococcal and coryneform endocarditis, it can also be used to treat drug-resistant staphylococcal infections, or if the above patients are allergic to penicillin, renal function tests and blood drug concentration monitoring are required to adjust the dosage or dosing interval or change the drug. 2. When antihistamines, buclizine, cyclizine, phenothiazines, thioxanthenes, trimethobenzylamine, etc. are used in combination with this product, they may mask ototoxic symptoms such as tinnitus, dizziness, and vertigo. 3. It is incompatible with alkaline solutions and may precipitate when it encounters heavy metals.
Specifications	0.8g (800,000 units) (calculated as C65H73Cl2N9O24)
Manufacturer	Zhejiang Zhebei Pharmaceutical Co., Ltd.

Norvancomycin Hydrochloride for Injection
Ingredients	Norvancomycin hydrochloride.
Specifications	0.4g (calculated as C65H73Cl2N9O24)
Manufacturer	North China Pharmaceutical Company.Ltd

Norvancomycin Hydrochloride for Injection
Ingredients	Norvancomycin hydrochloride.
Specifications	0.4g (400,000 units)

Registered Holders

Shenwei Pharmaceutical (Zhangjiakou) Co., Ltd.

China
Active
North China Pharmaceutical Huasheng Co., Ltd.

China
Active

Recommended Suppliers of Norvoncomycin hydrochloride

Hangzhou Hyper Chemicals Limited Contact Supplier

CN
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CAS No.: 213997-73-0

Grade: Pharmaceutical Grade

Content: 99.5%

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

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Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Norvoncomycin hydrochloride

CAS No.: 213997-73-0

Content: 99.00%

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Chongqing Chemdad Contact Supplier

CN
3 YRS

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Norvoncomycin hydrochloride

CAS No.: 213997-73-0

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Latest News on Norvoncomycin hydrochloride

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Guide of Norvoncomycin hydrochloride

Description
Basic Attributes
Characteristics
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

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