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Home > Encyclopedia > 4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside structure

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside 

structure
  • CAS No:

    37067-30-4

  • Formula:

    C18H21NO8

  • Chemical Name:

    4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside

  • Synonyms:

    2H-1-Benzopyran-2-one,7-[[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-;Coumarin,7-[(2-acetamido-2-deoxy-β-D-glucopyranosyl)oxy]-4-methyl-;7-[[2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one;4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside;4-Methylumbelliferyl-N-acetyl-β-glucosaminide;Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside;4-Methylumbelliferyl-N-acetylglucosaminide;4-Methylumbelliferyl-β-N-acetylglucosaminide;4-Methylumbelliferyl-β-D-N-acetylglucosaminide;13077-96-8;41650-35-5;58225-95-9;89298-62-4

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE is White Crystalline Solid

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside Basic Attributes

379.36

379.36

253-333-0

29321900

Characteristics

135

0.34

1.5±0.1 g/cm3

208-210 °C

732.2±60.0 °C at 760 mmHg

396.6±32.9 °C

1.632

DMF: 20 mg/mL, clear, colorless

−20°C

Safety Information

NONH for all modes of transport

3

22-24/25

Light Sensitive - Protect from Light

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside Use and Manufacturing

Uses

Fluorogenic substrate used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis.They include Tay Sachs disease, Sandhoff disease and other forms.Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm

2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-4-methyl-: INACTIVE

Computed Properties

Molecular Weight:379.4
XLogP3:-0.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:379.12671663
Monoisotopic Mass:379.12671663
Topological Polar Surface Area:135
Heavy Atom Count:27
Complexity:608
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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