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Alteplase

Alteplase structure

CAS No:
105857-23-6
Chemical Name:
Alteplase
Synonyms:
Alteplase;Activase (tn);Alteplase (genetical recombination);Alteplase (genetical recombination) (jan);Alteplase (usp/inn);D02837;PlasMinogen activator (huMan tissue-type protein Moiety) (9CI)
Categories:
Biochemical Engineering > Enzymes and Coenzymes Drugs

Description

Alteplase is a recombinant single-chain tissue plasminogen activator useful in the management of thrombosis in acute myocardial infarct. It reportedly causes no allergic reactions but requires intravenous infusion due to a short half-life. Alteplase is the only agent on the U.S. market indicated for the reduction of incidence of congestive heart failure following a heart attack.Alteplase (Activase) is a tissue plasminogenactivator (t-PA) produced by rDNA technology. It is a single-chain gly

Alteplase Use and Manufacturing

Tissue-type plasminogen activator; fibrinolytic.

Drug Function and Efficacy

This product is t-PA produced by genetic recombination technology. It has the same performance as natural tissue plasminogen activator (t-PA). It can activate plasminogen bound to fibrin and convert it into plasmin, which is much more effective than activating plasminogen in circulating blood. Its main function is to digest local fibrin clots.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Alteplase for injection
Specifications	20 mg/vial

Alteplase for injection
Ingredients	Active ingredient: Alteplase for injection. Excipients: Arginine, phosphoric acid, Tween 80 and water for injection
Indication	In patients with acute myocardial infarction, formal studies on the interaction of this product with commonly used drugs have not been conducted. The use of coumarin derivatives, oral anticoagulants, platelet aggregation inhibitors, unfractionated heparin, low molecular weight heparin and other drugs that inhibit coagulation before, during or within 24 hours after treatment with this product may increase the risk of bleeding (see instructions for details).
Specifications	20mg*1pc/box

Alteplase for injection
Ingredients	The main ingredient of this product is alteplase.
Specifications	50mg/vial

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105857-23-6

CAS No.: 105857-23-6

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Guide of Alteplase

Description
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
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