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ADL-5859

ADL-5859 structure

ADL-5859 

structure
  • CAS No:

    850173-95-4

  • Formula:

    C24H28N2O3.HCl

  • Chemical Name:

    ADL-5859

  • Synonyms:

    ADL-5859;N,N-Diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)benzamide hydrochloride;ADL5859 HCl;ADL5859 hydrochloride;Benzamide, N,N-diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)-, hydrochloride (1:1);N,N-Diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)benzamide hydrochlorideADL-5859

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

ADL5859 is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. IC50 value: 0.8 nM(Ki)Target: δ-opioid receptorADL-5859 (ADL5859) is an δ-opioid receptor agonist (Ki=0.84 nM, EC50=20 nM). ADL-5859 (ADL5859) is an agonist agent that selectively stimulates the δ-opioid receptor with potential application in a wide range of inflammatory, neuropathic and acute pain conditions. In addition, Delta agonists ar

ADL-5859 Basic Attributes

428.957

428.186676

-0

Characteristics

61.8

4.95130

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