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PKI-402

PKI-402 structure

CAS No:
1173204-81-3
Formula:
C29H34N10O3
Chemical Name:
PKI-402
Synonyms:
1-[4-[3-Ethyl-7-(morpholin-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]phenyl]-3-[4-[(4-methylpiperazin-1-yl)carbonyl]phenyl]urea;1-(4-(3-ethyl-7-morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)-3-(4-(1-methylpiperazine-4-carbonyl)phenyl)urea;1-(4-(3-ethyl-7-morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)-3-(4-(4-methylpiperazine-1-carbonyl)phenyl)urea;1-(4-(3-Ethyl-7-morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)-3-(4-(4-methylpiper
Categories:
Biochemical Engineering > Inhibitors

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PKI-402 Basic Attributes

Molecular Weight：

570.64546

Exact Mass：

570.28153498

UNII：

A5XSH56P2N

DSSTox ID：

DTXSID30657809

Characteristics

Density：

1.43

Boiling Point：

670.6±55.0 °C(Predicted)

Drug Information

MeSH Entry Terms：

PKI 402

PKI-402 Use and Manufacturing

A selective, reversible and ATP-competitive Class I PI3K inhibitor. PI3Kα, IC50=1 nM; PI3Kβ, IC50=7 nM; PI3Kγ, IC50=16 nM; PI3Kδ, IC50=14 nM.

Computed Properties

Molecular Weight:570.6
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:570.28153498
Monoisotopic Mass:570.28153498
Topological Polar Surface Area:134
Heavy Atom Count:42
Complexity:898
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 1173204-81-3

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CAS No.: 1173204-81-3

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