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Home > Encyclopedia > [4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone structure

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone 

structure
  • CAS No:

    1000669-72-6

  • Formula:

    C20H20N4O

  • Chemical Name:

    [4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone

  • Synonyms:

    [4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone;KW 2449;(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone;KW2449(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanonehydrochloride;[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone;{4-[(E)-2-(1H-Indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively.

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone Basic Attributes

332.41

332.163696

Characteristics

61

2.07

1.28

604.1±55.0 °C(Predicted)

319.1±31.5 °C

1.723

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