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ZM 336372

ZM 336372 structure

CAS No:
208260-29-1
Formula:
C23H23N3O3
Chemical Name:
ZM 336372
Synonyms:
N-[5-(3-DIMETHYLAMINOBENZAMIDO)-2-METHYLPHENYL]-4-HYDROXYBENZAMIDE;ZM 336372;3-(DIMETHYLAMINO)-N-[3-[(4-HYDROXYBENZOYL)-AMINO]-4-METHYLPHENYL]BENZAMIDE;Zinc00581684;3-(diMethylaMino)-N-(3-(4-hydroxybenzaMido)-4-Methylphenyl)benzaMide;Benzamide, 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]-;ZM 3363723-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide;ZM 336372, >=98%
Categories:
Biochemical Engineering > Inhibitors

Description

ZM 336372 is a potent inhibitor of the protein kinase c-Raf. The IC50 value is 0.07 μM in the standard assay, which contains 0.1 mM ATP.

3-(dimethylamino)-N-[3-[[(4-hydroxyphenyl)-oxomethyl]amino]-4-methylphenyl]benzamide is a member of benzamides.

ZM 336372 Basic Attributes

Molecular Weight：

389.45

Exact Mass：

389.173950

DSSTox ID：

DTXSID70274478

Characteristics

PSA：

81.7

XLogP3：

3.7

Appearance：

white to beige

Density：

1.3±0.1 g/cm3

Boiling Point：

484.4°C at 760 mmHg

Flash Point：

246.8±28.7 °C

Refractive Index：

1.704

Water Solubility：

DMSO: >5mg/mL (warmed)

Storage Conditions：

-20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

Drug Information

MeSH Entry Terms：

N-(5-(3-dimethylaminobenzamido)-2-methylphenyl)-4-hydroxybenzamide

ZM 336372 Use and Manufacturing

It is small molecule tyrosine kinase modulator.

Computed Properties

Molecular Weight:389.4
XLogP3:3.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:389.17394160
Monoisotopic Mass:389.17394160
Topological Polar Surface Area:81.7
Heavy Atom Count:29
Complexity:560
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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ZM 336372

CAS No.: 208260-29-1

Content: 99%

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