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KY0211

KY0211 structure

CAS No:
1118807-13-8
Formula:
C18H17ClN2O3S
Chemical Name:
KY0211
Synonyms:
KY0211;KY02111;KY02111 /KY-02111;N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide;Benzenepropanamide, N-(6-chloro-2-benzothiazolyl)-3,4-dimethoxy-;KY0211 N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide;N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamideKY02111;KY02111, >=98%
Categories:
Biochemical Engineering > Inhibitors

Description

KY02111 is a small molecule which can promote differentiation of hPSCs to cardiomyocytes.IC50 value: Target: Wnt signaling inhibitorKY02111 Induces downregulation of Wnt signaling target genes; inhibits canonical Wnt signaling in a manner distinct from other known Wnt inhibitors.KY02111 (10 μM) increases the ratio of beating cardiac colonies as much as 70%-94% in cell aggregates of two hESC lines (KhES-1 and KhES-3), four hiPSC lines (253G1, IMR90-1, IMR90-4, and RCHIPC0003), and a mouse

KY0211 Basic Attributes

Molecular Weight：

376.85718

Exact Mass：

376.064850

EC Number：

-0

UNII：

6AXH36YF6M

DSSTox ID：

DTXSID80429194

Characteristics

PSA：

88.7

XLogP3：

4.3

Appearance：

white to beige

Density：

1.362±0.06 g/cm3(Predicted)

Refractive Index：

1.661

Water Solubility：

DMSO: soluble10mg/mL, clear

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 127 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

KY02111

Computed Properties

Molecular Weight:376.9
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:376.0648413
Monoisotopic Mass:376.0648413
Topological Polar Surface Area:88.7
Heavy Atom Count:25
Complexity:456
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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KY02111

CAS No.: 1118807-13-8

Content: 99%

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Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

1118807-13-8 N-(6-chloro-1,3-benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide

CAS No.: 1118807-13-8

Grade: Industrial Grade

Content: 95%

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