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γ-Secretase inhibitor IX

γ-Secretase inhibitor IX structure

γ-Secretase inhibitor IX 

structure
  • CAS No:

    208255-80-5

  • Formula:

    C23H26F2N2O4

  • Chemical Name:

    γ-Secretase inhibitor IX

  • Synonyms:

    Glycine,N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-,1,1-dimethylethyl ester,(2S)-;Glycine,N-[(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-,1,1-dimethylethyl ester,(2S)-;DAPT (enzyme inhibitor);DAPT;γ-Secretase inhibitor IX;GSI-IX;N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester;N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine tert-butyl ester;LY 374973

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

DAPT is a γ-secretase inhibitor with IC50s of 115 and 200 nM for total Aβ and Aβ42, respectively.

γ-Secretase inhibitor IX Basic Attributes

432.464

432.46

2924299090

Characteristics

84.5

3.7

white solid

1.2±0.1 g/cm3

612.2°C at 760 mmHg

324.1±31.5 °C

1.535

DMSO: ~18 mg/mL

2-8°C

Safety Information

NONH for all modes of transport

3

24/25

γ-Secretase inhibitor IX Use and Manufacturing

A potent and specific inhibitor of γ-secretase.

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