γ-Secretase inhibitor IX
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γ-Secretase inhibitor IX
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CAS No:
208255-80-5
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Formula:
C23H26F2N2O4
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Chemical Name:
γ-Secretase inhibitor IX
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Synonyms:
Glycine,N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-,1,1-dimethylethyl ester,(2S)-;Glycine,N-[(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-,1,1-dimethylethyl ester,(2S)-;DAPT (enzyme inhibitor);DAPT;γ-Secretase inhibitor IX;GSI-IX;N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester;N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine tert-butyl ester;LY 374973
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CAS No:
Description
DAPT is a γ-secretase inhibitor with IC50s of 115 and 200 nM for total Aβ and Aβ42, respectively.
Characteristics
84.5
3.7
white solid
1.2±0.1 g/cm3
612.2°C at 760 mmHg
324.1±31.5 °C
1.535
DMSO: ~18 mg/mL
2-8°C
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