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Corilagin

Corilagin structure

CAS No:
23094-69-1
Formula:
C27H22O18
Chemical Name:
Corilagin
Synonyms:
β-D-Glucopyranose,cyclic 3,6-[(1R)-4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate] 1-(3,4,5-trihydroxybenzoate);Glucopyranose,cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxydiphenate) 1-gallate,β-D-;Corilagin;β-D-Glucopyranose,cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate),(R)-;8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin,β-D-glucopyranose deriv.;Corillagin;1646808-35-6
Categories:
Biochemical Engineering > Chinese Herbs

Description

Corilagin, a gallotannin, is isolated from Caesalpinia coriaria (Jacq.) Willd. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows good anti-tumor activity on hepatocellular carcinoma and ovarian cancer. Corilagin shows a low level of toxicity toward normal cells and tissues[1].

Corilagin Basic Attributes

Molecular Weight：

634.45

Exact Mass：

634.45

Characteristics

PSA：

310.66000

XLogP3：

-0.29650

Appearance：

Off-White Solid

Density：

2.1±0.1 g/cm3

Melting Point：

206-207 °C @ Solvent: Water

Boiling Point：

1297.4ºC at 760mmHg

Flash Point：

418.8±27.8 °C

Refractive Index：

1.881

Water Solubility：

H2O: soluble1mg/mL, clear, colorless

Storage Conditions：

-20°C Freezer

Vapor Pressure：

0mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

Corilagin Use and Manufacturing

Thrombolytic

Drug Function and Efficacy

Clears away heat and detoxifies, removes dampness and relieves jaundice

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Leaf beads
Ingredients	The main chemical components of Phyllanthus urinaria are gallic acid, methoxy succinic acid, succinic acid, carotene, camellia sinensis, ferulic acid, lignans, quercetin, brevipeinic acid, corilagin, flavonoids, dehydrochebulic acid, rutin, alkaloids, rutin, brevipeinic acid ethyl ester, brevipeinic acid methyl ester, geraniol, brevipeinic acid and dehydrochebulic acid trimethyl ester, etc. Gallic acid is the main active ingredient and has antiviral effects.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Sugar-coated tablets (core weight 0.3 g)
Manufacturer	Dali Bai Autonomous Prefecture Traditional Chinese Medicine Pharmaceutical Co., Ltd.

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Corilagin

CAS No.: 23094-69-1

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Guide of Corilagin

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
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Corilagin

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