 Home > Encyclopedia > 4-Hydroxylthiocoumarin

4-Hydroxylthiocoumarin

4-Hydroxylthiocoumarin structure

CAS No:
16854-67-4
Formula:
C9H6O2S
Chemical Name:
4-Hydroxylthiocoumarin
Synonyms:
4-HYDROXY-2H-THIOCHROMEN-2-ONE;AKOS AU-SVL-37-03;CHEMBRDG-BB 5102960;4-Hydroxy thiocoumarin;4-hydroxy-2H-benzothiopyran-2-one;4-Hydroxythiocoumarin;4-HYDROXYLTHIOCOUMARIN;4-hydroxy-2H-benzothiopyran-2-one，4-hydroxyl-thio-coumarin
Categories:
Agrochemicals > Pesticide Intermediates

Request for Quotation

4-Hydroxylthiocoumarin Basic Attributes

Molecular Weight：

178.21

Exact Mass：

178.008850

HScode：

2932209090

Characteristics

PSA：

62.6

XLogP3：

2.23

Density：

1.478±0.06 g/cm3(Predicted)

Melting Point：

209 °C(Solv: water (7732-18-5))

Boiling Point：

304.9±42.0 °C(Predicted)

Flash Point：

138.2±27.9 °C

Refractive Index：

1.726

Safety Information

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

4-Hydroxylthiocoumarin Use and Manufacturing

Methods of Manufacturing

The preparation method is that thiophenol, malonic acid and phosphorus oxychloride are heated to reflux for 0.5h in a reaction pot to obtain dithiophenyl malonate, which is cooled, washed with water and washed with 10% sodium hydroxide solution to obtain crystals. The crystal is reacted with anhydrous aluminum trichloride at a temperature of 180-185°C, reacted for 25 minutes, cooled, decomposed with ice water and hydrochloric acid, cooled, filtered, dissolved in a 10% sodium hydroxide solution, and then precipitated with hydrochloric acid to obtain the product.

Uses

4-Hydroxy-2H-benzothiopyran-2-one, also known as 4-hydroxy-1-thiocoumarin, is an intermediate of the rodenticide thiamine.

Computed Properties

Molecular Weight:178.21
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:178.00885060
Monoisotopic Mass:178.00885060
Topological Polar Surface Area:62.6
Heavy Atom Count:12
Complexity:235
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Diethyl carbonate

Dimethyl carbonate

Recommended Suppliers of 4-Hydroxylthiocoumarin

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Most Professional Manufacturer Supply High Quality 4-Hydroxylthiocoumarin CAS 16854-67-4

CAS No.: 16854-67-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

4-Hydroxylthiocoumarin

CAS No.: 16854-67-4

Content: 99.00%

Inquiry