alpha, oMega-Dipropionic acid triethylene glycol
-
alpha, oMega-Dipropionic acid triethylene glycol
structure -
-
CAS No:
31127-85-2
-
Formula:
C12H22O8
-
Chemical Name:
alpha, oMega-Dipropionic acid triethylene glycol
-
Synonyms:
alpha, oMega-Dipropionic acid triethylene glycol;HOOC-PEG3-COOH;α,ω-Dipropionic acid triethylene glycol;4,7,10,13-Tetraoxahexadecanedioic acid;Bis-PEG4-acid;Bis-PEG5-acid;4,7,10,13-Tetraoxa-hexadecan-1,16-dicarbonsaeure;4,7,10,13-Tetraoxahexadecane-1,16-dioic acid
- Categories:
-
CAS No:
alpha, oMega-Dipropionic acid triethylene glycol Use and Manufacturing
To a solution of compound 71(5.9 g, 20.05 mmol) in DMF (50 mL) were addedDIEA (3.6 mL, 20.67 mmol) and dropwise over 10 mm a solution of benzyl bromide(2.43 mL, 20.05 mmol) in DMF (50 mL). The reaction medium was stirred for 20 h atRT, quenched with 1 N HCI (500 mL) and extracted twice with EtOAc (200 mL). Thecombined organic phases were dried over Mg504, filtered, concentrated in vacuoand purified by two consecutive flash chromatographies on 400 g and 100 g of silicagel (gradient elution DCM/MeOH) to give 2.7 g of compound 72 as a pale green oil(35%).RMN 1H (300 MHz, oe in ppm, DMSO-d6): 2.42 (m, 2 H) ; 2.60 (t, J = 6.5 Hz, 2 H);3.47 (5, 6 H); 3.49 (5, 6 H); 3.59 (m, 2 H); 3.66 (d, J = 6.5 Hz, 2 H); 5.10 (5, 2 H);7.29 to 7.41 (m, 5 H).To compound 70 (8.05 g, 19.8 mmmol) was added formic acid (40 mL, 1.04 mol). The reaction medium was stirred for 1 d at RT, concentrated in vacuo and coevaporated with EtOAc (20 mL) to give 5.9 g of compound 71 as a colorless oil(quant.).RMN 1H (300 MHz, oe in ppm, DMSO-d6): 2.44 (t, J = 6.5 Hz, 4 H); 3.48 (5, 8 H); 3.50 (s, 4 H); 3.59 (d, J = 6.5 Hz, 4 H); 12.25 (broad m, 2 H).
Computed Properties
Molecular Weight:294.30
XLogP3:-1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:15
Exact Mass:294.13146766
Monoisotopic Mass:294.13146766
Topological Polar Surface Area:112
Heavy Atom Count:20
Complexity:230
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of alpha, oMega-Dipropionic acid triethylene glycol
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 31127-85-2Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
Polyethylene glycol octyl ether acid phosphate
31800-88-1
-
Aniline,4,4′-methylenedi-,polymer with 1,2,4-benzenetricarboxylic acid cyclic 1,2-anhydride,dimethyl terephthalate,ethylene glycol and 1,3,5-tris(2-hydroxyethyl)-s-triazine-2,4,6(1H,3H,5H)-trione
25950-45-2
-
Octadecanoic acid, mixed esters with myristic acid and neopentyl glycol
68585-01-3
-
(3-BROMOMETHYLPHENYL)BORONIC ACID NEOPENTYL GLYCOL ESTER Formula
143805-78-1
-
4-Chlorobenzonitrile-2,5-diboronic acid neopentyl glycol ester Formula
1072944-28-5
-
3-BROMO-2-CYANOPHENYLBORONIC ACID NEOPENTYL GLYCOL ESTER Formula
883899-07-8
-
2-Butenedioic acid (2Z)-, mixed esters with 2-ethyl-1-hexanol and propylene glycol Structure
68876-94-8
-
alpha-aMine-oMega-propionic acid hexaethylene glycol Structure
905954-28-1
-
What is Triethylene glycol mono(p-nonylphenyl) ether
51437-95-7
-
What is Triethylene glycol monopropyl ether
23305-64-8
alpha, oMega-Dipropionic acid triethylene glycol
SDSRequest for Quotation