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Home > Encyclopedia > alpha-aMine-oMega-propionic acid hexaethylene glycol

alpha-aMine-oMega-propionic acid hexaethylene glycol

alpha-aMine-oMega-propionic acid hexaethylene glycol structure

alpha-aMine-oMega-propionic acid hexaethylene glycol 

structure
  • CAS No:

    905954-28-1

  • Formula:

    C15H31NO8

  • Chemical Name:

    alpha-aMine-oMega-propionic acid hexaethylene glycol

  • Synonyms:

    alpha-aMine-oMega-propionic acid hexaethylene glycol;H2N-PEG6-CH2CH2COOH;α-aMine-ω-propionic acid hexaethylene glycol;1-Amino-3,6,9,12,15,18-hexaoxaheneicosan-21-oic acid;Amino-PEG6-acid;amino-dPEG 6-acid;Amino-PEG6-propionic acid;NH2-PEG6-COOH

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

alpha-aMine-oMega-propionic acid hexaethylene glycol Basic Attributes

353.40854

353.20500

Characteristics

118.70000

0.21970

1.130±0.06 g/cm3(Predicted)

Safety Information

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Computed Properties

Molecular Weight:353.41
XLogP3:-4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:20
Exact Mass:353.20496695
Monoisotopic Mass:353.20496695
Topological Polar Surface Area:119
Heavy Atom Count:24
Complexity:268
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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