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Pixantrone maleate

Pixantrone maleate structure

Pixantrone maleate 

structure
  • CAS No:

    144675-97-8

  • Formula:

    C17H19N5O2.2C4H4O4

  • Chemical Name:

    Pixantrone maleate

  • Synonyms:

    Benz[g]isoquinoline-5,10-dione,6,9-bis[(2-aminoethyl)amino]-,(2Z)-2-butenedioate (1:2);Benz[g]isoquinoline-5,10-dione,6,9-bis[(2-aminoethyl)amino]-,(Z)-2-butenedioate (1:2);BBR 2778;Pixantrone maleate;Pixantrone dimaleate;Pixuvri

Description

Blue Solid

Pixantrone maleate Basic Attributes

441.43722

557.175792

1308068-626-2

Characteristics

272

1.85660

192°

650ºC at 760mmHg

346.9ºC

8.89E-17mmHg at 25°C

Pixantrone maleate Use and Manufacturing

Pixantrone is an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone (M373425) and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer's disease.

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