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Home > Encyclopedia > 2-chloro-5-(trifluoromethyl)-4-iodopyridine

2-chloro-5-(trifluoromethyl)-4-iodopyridine

2-chloro-5-(trifluoromethyl)-4-iodopyridine structure

2-chloro-5-(trifluoromethyl)-4-iodopyridine 

structure
  • CAS No:

    505084-55-9

  • Formula:

    C6H2ClF3IN

  • Chemical Name:

    2-chloro-5-(trifluoromethyl)-4-iodopyridine

  • Synonyms:

    2-chloro-5-(trifluoromethyl)-4-iodopyridine;2-Chloro-4-iodo-5-(trifluoromethyl)pyridine;2-Chloro-4-iodo-5-(trifluoroMethyl)pyridine, tech. 90%;6-Chloro-4-iodo-alpha,alpha,alpha-trifluoro-3-picoline;2-chloro -4-iodine -5- threefluorineMethyl pyridine;Pyridine, 2-chloro-4-iodo-5-(trifluoromethyl)-

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

2-chloro-5-(trifluoromethyl)-4-iodopyridine Basic Attributes

307.4394596

306.887238

-0

DTXSID40378715

2933399090

Characteristics

12.9

3.3

Solid

2.0±0.1 g/cm3

126.0 to 130.0 °C

257.6°C at 760 mmHg

109.6±27.3 °C

1.540

Safety Information

IRRITANT

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-chloro-5-(trifluoromethyl)-4-iodopyridine Use and Manufacturing

2-Chloro-4-iodo-5-(trifluoromethyl)pyridine is used in preparation of pyridine-2,4-diamine derivatives as FAK inhibitors for the treatment of arthritis, inflammatory and immune disorders.

Computed Properties

Molecular Weight:307.44
XLogP3:3.3
Hydrogen Bond Acceptor Count:4
Exact Mass:306.88726
Monoisotopic Mass:306.88726
Topological Polar Surface Area:12.9
Heavy Atom Count:12
Complexity:163
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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