Bisbenzimide
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Bisbenzimide
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CAS No:
23491-52-3
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Formula:
C27H28N6O
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Chemical Name:
Bisbenzimide
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Synonyms:
2,6′-Bi-1H-benzimidazole,2′-(4-ethoxyphenyl)-6-(4-methyl-1-piperazinyl)-;2,5′-Bibenzimidazole,2′-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2,5′-Bi-1H-benzimidazole,2′-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2′-(4-Ethoxyphenyl)-6-(4-methyl-1-piperazinyl)-2,6′-bi-1H-benzimidazole;2-[2-(4-Ethoxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazinyl)benzimidazole;HOE 33342;Hoechst 33342;Bisbenzimide;Ho 342;NSC 334072;BXI 72;Hoechst H 33342;2′-(4-Ethoxyphenyl)-6-(4-methylpiperazin-1-yl)-1H,3′H-2,5′-bibenzimidazole;2-(4-Ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
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CAS No:
Description
Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole is a bibenzimidazole and a N-methylpiperazine. It has a role as a fluorochrome. It derives from a pibenzimol.
Characteristics
73.1
7.13970
Yellow-green powder.
1.274±0.06 g/cm3(Predicted)
268ºC
H2O: soluble 20mg/mL
2-8°C
dni-hmn-hla 300 nmol/L CRNGDP 13,2389,1992
Safety Information
NONH for all modes of transport
3
22-37/38-36/37/38-20/21/22-37-35
22-36/37-24/25-36-26-45-36/37/39
DT4200000
Xn,C
Stable under normal temperatures and pressures.
P280-P301 + P312 + P330
H302-H315-H335-H341
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P308+P313, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)|Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military. (See all compounds classified as Radiation-Protective Agents.)|Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells. (See all compounds classified as Radiation-Sensitizing Agents.)
2,5'-bi-1h-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-, trihydrochloride
Bisbenzimide Use and Manufacturing
Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.
Computed Properties
Molecular Weight:452.6
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:452.23245954
Monoisotopic Mass:452.23245954
Topological Polar Surface Area:73.1
Heavy Atom Count:34
Complexity:664
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
