Lead chromate oxide (Pb2(CrO4)O)

5.5e+02 g/mol

547.86838 g/mol

Red crystalline powder

97.3 Ų

6.63 g/cm³

920 °C

Insoluble water|Soluble in acids, alkalis

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects /Lead Chromate/|Store in a secure poison location. ... Lead chromate must be stored to avoid contact with oxidizers (such as perchlorates, peroxides, permanganates, chlorates, and nitrates) and chemically active metals (such as potassium, sodium, magnesium, zinc and ferric ferrocyanide), since violent reactions occur. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. /Lead Chromate/|PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

Stable under recommended storage conditions. /Lead Chromate/

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D008, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.|Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D007, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Chromium/|Product: Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber; Contaminated packaging: Dispose of as unused product. /Lead Chromate/|Chemical Treatability of Lead; Concentration Process: Biological Treatment; Chemical Classification: Metal; Scale of Study: Respirometer Study; Results of Study: Oxygen uptake inhibited. /Inorganic lead cmpd/|For more Disposal Methods (Complete) data for LEAD CHROMATE OXIDE (18 total), please visit the HSDB record page.

Incompatible materials: Organic materials, powdered metals /Lead Chromate/|Strong oxidizers, hydrogen peroxide, acids. /Lead/|Combustible, organic, or other readily oxidizable materials (paper, wood, sulfur, aluminum, plastics, etc.); corrosive to metals. /Chromic acid and chromates/|Hydrazine is decomposed explosively by chromates and chromic anhydride. /Chromates/

National Toxicology Program. Eleventh Report on Carcinogens (2005). The Report on Carcinogens is an informational scientific and public health document that identifies and discusses substances (including agents, mixtures, or exposure circumstances) that may pose a carcinogenic hazard to human health. Lead and Lead Compounds are listed as reasonably anticipated to be human carcinogens. /Lead and Lead Compounds/[Available from, as of July 31, 2009: http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s101lead.pdf]|National Toxicology Program. Eleventh Report on Carcinogens (2005). The Report on Carcinogens is an informational scientific and public health document that identifies and discusses substances (including agents, mixtures, or exposure circumstances) that may pose a carcinogenic hazard to human health. Chromium Hexavalent Compounds are listed as known to be human carcinogens. /Chromium Hexavalent Compounds/[Available from, as of July 31, 2009: http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s045chro.pdf]

|Danger|H317: May cause an allergic skin reaction [Warning Sensitization, Skin]|P201, P202, P260, P261, P271, P272, P280, P281, P302+P352, P304+P340, P308+P313, P311, P314, P321, P333+P313, P363, P403+P233, P405, and P501|H350: May cause cancer [Danger Carcinogenicity]|P201, P202, P260, P273, P281, P308+P313, P314, P391, P405, and P501

Eye/face protection: Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). /Lead Chromate/|Skin protection: Handle with gloves. /Lead Chromate/|Body Protection: Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. /Lead Chromate/|Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). /Lead Chromate/|For more Personal Protective Equipment (PPE) (Complete) data for LEAD CHROMATE OXIDE (26 total), please visit the HSDB record page.

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. /Lead Chromate/|Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. /Lead Chromate/|Self-contained breathing apparatus with a full facepiece, operated in pressure-demand or other positive pressure mode. /Inorganic lead/|NFPA recommends the use of water on fire. /Lead Chromate/|For more Fire Fighting Procedures (Complete) data for LEAD CHROMATE OXIDE (7 total), please visit the HSDB record page.

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided; Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. /Lead Chromate/|... Treatment of wastewater from a tetraethyl lead manufacturing process /was described/. Two major categories of waste were inorganic lead wastewaters and organic lead wastewaters. After sedimentation in a holding basin to recover solid lead and lead oxide, the inorganic lead waste fraction (66.1 mg/L) was effectively treated by coagulation with ferric and ferrous sulfate. /Inorganic lead/|Evacuate persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Collect powdered material in the most convenient and safe manner and deposit in sealed containers. Ventilate area after cleanup is complete. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. /Lead Chromate/|Cr(VI) cmpd in waste sludge are completely removed by redn by carbon at 600 °C. /Chromium VI/|For more Cleanup Methods (Complete) data for LEAD CHROMATE OXIDE (6 total), please visit the HSDB record page.

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. /Lead Chromate/|Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed. /Lead Chromate/|Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. /Lead Chromate/|Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. /Lead Chromate/|For more Preventive Measures (Complete) data for LEAD CHROMATE OXIDE (25 total), please visit the HSDB record page.

PRECAUTIONS FOR "CARCINOGENS": Procurement ... of unduly large amt ... should be avoided. To avoid spilling, carcinogens should be transported in securely sealed glass bottles or ampoules, which should themselves be placed inside strong screw-cap or snap-top container that will not open when dropped & will resist attack from the carcinogen. Both bottle & the outside container should be appropriately labelled. ... National post offices, railway companies, road haulage companies & airlines have regulations governing transport of hazardous materials. These authorities should be consulted before ... material is shipped. /Chemical Carcinogens/|PRECAUTIONS FOR "CARCINOGENS": When no regulations exist, the following procedure must be adopted. The carcinogen should be enclosed in a securely sealed, watertight container (primary container), which should be enclosed in a second, unbreakable, leakproof container that will withstand chem attack from the carcinogen (secondary container). The space between primary & secondary container should be filled with absorbent material, which would withstand chem attack from the carcinogen & is sufficient to absorb the entire contents of the primary container in the event of breakage or leakage. Each secondary container should then be enclosed in a strong outer box. The space between the secondary container & the outer box should be filled with an appropriate quantity of shock-absorbent material. Sender should use fastest & most secure form of transport & notify recipient of its departure. If parcel is not received when expected, carrier should be informed so that immediate effort can be made to find it. Traffic schedules should be consulted to avoid ... arrival on weekend or holiday ... /Chemical Carcinogens/

Irritates the respiratory tract. ... Irritation of nose, throat, or bronchial tubes can also occur, with cough and/or wheezing. Skin contact with concentrated lead chromate can cause burns, deep ulcers, or an allergic skin rash. /Lead Chromate/|Chromic acid mist & chromate dusts may cause severe irritation of the nose, throat, bronchial tubes, and lung. /Chromic acid mist & chromate dusts/

Permissible Exposure Limit: (1) The employer shall assure that no employee is exposed to lead at concentrations greater than fifty micrograms per cubic meter of air (50 ug/cu m) averaged over an 8-hr period. (2) If an employee is exposed to lead for more than 8 hr in any work day, the permissible exposure limit, as a time weighted average (TWA) for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/cu m)=400 divided by the number of hours worked in the day. (3) When respirators are used to supplement engineering and work practice controls to comply with the PEL and all the requirements of paragraph (f) have been met, employee exposure, for the purpose of determining whether the employer has complied with the PEL, may be considered to be at the level provided by the protection factor of the respirator for those periods the respirator is worn. Those periods may be averaged with exposure levels during periods when respirators are not worn to determine the employee's daily TWA exposure. /Lead means metallic lead, all inorganic lead compounds, and organic lead soaps. Excluded from this definition are all other organic lead compounds./|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 1 mg/cu m. /Chromium metal and insoluble salts, as Cr/|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 0.5 mg/cu m. /Chromium(II) compounds, as Cr/|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 0.5 mg/cu m. /Chromium(III) compounds, as Cr/|Permissible Exposure Limit: Table Z-2 Acceptable Ceiling Concentration: 1 mg/10 cu m. /Chromic acid and chromates (as CrO3)/

Recommended Exposure Limit: 8-hour Time-Weighted Average: 0.5 mg Cr/cu m. /Chromium metal, chromium(II) and chromium(III) compounds/|Recommended Exposure Limit: 8-hour Time-Weighted Average: 0.0002 mg Cr(VI)/cu m. NIOSH considers all Cr(VI) compounds (including chromic acid, tert-butyl chromate, zinc chromate, and chromyl chloride) to be potential occupational carcinogens. /All hexavalent chromium (Cr(VI) compounds/|NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concentration. /Chromic acid and chromates/

... Substances for which a Federal Register notice has been published that included consideration of the serious health effects, including cancer, from ambient air exposure to the substance. Chromium is included on this list. /Chromium/|Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Chromium compounds is included on this list. /Chromium compounds/

D008; A waste containing lead may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. /Lead/|D007; A waste containing chromium may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. /Chromium/

D008; A solid waste containing lead may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Lead/|D007; A solid waste containing chromium may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Chromium/

IDENTIFICATION AND USE: Lead chromate oxide is a red crystalline powder. It is used as a pigment. HUMAN EXPOSURE AND TOXICITY: Signs of exposure: Respiratory irritations; nasal septum irritations; leukocytosis, leukopenia, monocytosis, eosinophilia; eye injury, conjunctivitis; and skin ulcers, sensitization dermatitis. Target organs which are affected include blood, lung, respiratory system, liver, kidneys, eyes, and skin. ANIMAL STUDIES: There is no data.

NIOSH (NOES Survey 1981-1983) has statistically estimated that 697 workers (306 of these are female) were potentially exposed to lead chromate oxide in the US(1).

The metabolism of lead follows closely that of calcium, particularly with regard to its deposition in & mobilization from bone. ... When bone marrow activity is increased ... calcium mobilization may take place, causing hypercalcemia & osteolysis. ... Lead may also be liberated. ... /Inorganic lead/

Body burden of lead, as assessed by lead excretion 24 hr after Ca-EDTA administration, was increased in 37% of the workers with a mean value of 607 + or - 425 ug. Mean blood lead was 32 + or - 14 ug/dL. Creatinine clearance was normal in all workers. Maximal urinary concentrating ability was abnormal in a significant fraction (52%) of the men. /Inorganic lead/

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/|EXPTL THERAPY: THERAPEUTIC DOSES OF THIAMINE MAY BE OF VALUE IN PREVENTION & TREATMENT OF LEAD POISONING IN CATTLE & IN OTHER ANIMALS, OR HUMANS EXPOSED TO HIGH ENVIRONMENTAL LEVELS OF LEAD.|For more Antidote and Emergency Treatment (Complete) data for LEAD CHROMATE OXIDE (10 total), please visit the HSDB record page.

/SIGNS AND SYMPTOMS/ Signs of exposure: Respiratory irritations; nasal septum irritations; leukocytosis, leukopenia, monocytosis, eosinophilia; eye injury, conjunctivitis; skin ulcers, sensitization dermatitis.|/SIGNS AND SYMPTOMS/ Target organs which are affected include blood, lung, respiratory system, liver, kidneys, eyes, and skin.|/SIGNS AND SYMPTOMS/ SYMPTOMATOLOGY: B. Lead encephalopathy in chronic lead poisoning. 1) Headache and insomnia. 2) Persistent vomiting, which is sometimes projectile. A typical lead colic may or may not be present. 3) Visual disturbances, choked optic disks. 4) Irritability, restlessness, delirium, hallucinations. 5) Convulsions and coma. 6) The intracranial pressure is characteristically high. The cerebrospinal fluid is generally unremarkable except for and elevation of total protein. 7) Death from exhaustion and respiratory failure. The mortality rate is high; Recovery is slow and frequently incomplete. /Lead cmpd/

Lead chromate oxide (Pb2(CrO4)O): ACTIVE