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Dermatan sulfate

Dermatan sulfate structure

CAS No:
24967-94-0
Formula:
H2O4S.xUnspecified
Chemical Name:
Dermatan sulfate
Synonyms:
Dermatan,hydrogen sulfate (ester);Chondroitinsulfuric acids,type B;Dermatan sulfate;Chondroitin sulfate B;Chondroitinsulfuric acid type B;Chondroitinsulfuric acid,type B;β-Heparin;Chondroitinsulfuric acid B;Dermatan polysulfate;Dermatan 4-sulfate;Dermatan sulphate;Chondroitin sulfate type B;MF 701;Desmin 370;DS 435;Dermatan hydrogen sulfate;MF 701 (polysaccharide);DS 435 (polysaccharide);Dermatan surfate;9045-59-4;9083-19-6;11120-35-7;11129-22-9;11129-23-0;42616-56-8;177697-01-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Dermatan sulfate polyanion is the conjugate base of dermatan sulfate, obtained by deprotonation of carboxy and sulfate groups. It is a monocarboxylic acid anion, an organosulfate oxoanion and a polyanionic polymer. It is a conjugate base of a dermatan sulfate.|A naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue. It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5. (from Merck, 12th ed)

Dermatan sulfate Basic Attributes

Molecular Weight：

475.4 g/mol

Exact Mass：

475.06319014 g/mol

EC Number：

246-552-8

DSSTox ID：

DTXSID40179683

ATC Code：

B - Blood and blood forming organs

Characteristics

PSA：

273 Å²

Drug Information

MeSH：

Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)

MeSH Entry Terms：

beta Heparin

Computed Properties

Molecular Weight:475.4
XLogP3:-4.3
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:5
Exact Mass:475.06319014
Monoisotopic Mass:475.06319014
Topological Polar Surface Area:273
Heavy Atom Count:31
Formal Charge:-2
Complexity:737
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes